血清指标联合诊断糖尿病合并冠心病的临床价值

The Clinical Value of Combined Serum Index in Diagnosing Diabetes With Coronary Heart Disease

目的 探讨2型糖尿病合并冠心病患者以血清胆红素、糖化血红蛋白、血脂指标联合检验的效果与临床应用价值。方法 选择2019年12月—2020年12月于枣庄市精神卫生中心接受治疗的2型糖尿病合并冠心病患者75例作为观察组,选择同期枣庄市精神卫生中心收诊治疗单纯2型糖尿病患者75例作为对照组,均进行血脂、血清胆红素、糖化血红蛋白指标的检验。对比两组患者检验结果差异,并探讨观察组患者中不同评分结果各项指标的差异。结果 观察组患者总胆红素(total bilirubin,TBIL)、高密度脂蛋白(high-density lipoprotein,HDL-C)指标均明显低于对照组,糖化血红蛋白(hemoglobin A1c,Hb A1c)、总胆固醇(total cholesterol,TC)、三酰甘油(triglyceride,TG)、低密度的脂蛋白(low-density lipoprotein,LDL-C)指标均明显高于对照组(P <0.05)。观察组中,高危评分患者TBIL、HDL-C检验结果明显低于中危、低危患者,HbAlc、TC、TG、LDL-C检验结果高于中危、低危患者(P <0.05)。结论 通过血清胆红素、糖化血红蛋白、血脂指标联合检验2型糖尿病合并冠心病能够为临床提供可靠数据支持,便于疾病进一步诊断与病情分析。

Objective To explore the effect and clinical value of combined detection of serum bilirubin,glycosylated hemoglobin and blood lipids in patients with type 2 diabetes mellitus and coronary heart disease.Methods A total of 75 patients with type 2 diabetes complicated with coronary heart disease who were treated in Zaozhuang Mental Health Center from December 2019to December 2020 were selected as the observation group,and 75patients with simple type 2 diabetes who were treated in Zaozhuang Mental Health Center during the same period were selected as the control group.The indexes of blood lipid,serum bilirubin and glycosylated hemoglobin were tested..The test results of the two groups were compared.In addition,to observe the differences of different scores and indexes in patients with combined coronary heart disease.Results The indexes of total bilirubin(TBIL) and high-density lipoprotein(HDL-C) in the observation group were significantly lower than those in the control group,and the indexes of HbA1c,total cholesterol(TC),triglyceride(TG) and low-density lipoprotein(LDL-C) in the observation group were significantly higher than those in the control group(P<0.05).The results of TBIL and HDL-C in patients with high risk score were significantly lower than those in patients with medium and low risk,and the results of HbAlc,TC,TG and LDL-C were higher than those in patients with medium and low risk(P<0.05).Conclusion Combined detection of serum bilirubin,glycosylated hemoglobin and blood lipids can provide reliable data support for clinical diagnosis of type 2 diabetes mellitus complicated with coronary heart disease.