摘要
胆道恶性肿瘤是一种高度侵袭性的恶性肿瘤,近年来发病率逐年升高,大多数患者就诊时无手术机会,且传统全身化疗疗效有限。近年来,肿瘤精准治疗理念指导下的靶免治疗在晚期胆道恶性肿瘤中取得了显著进展,本文就胆道恶性肿瘤的精准诊疗进行述评,并对临床应用进行讨论。
Biliary tract carcinoma(BTC)is a highly invasive malignant tumor,and its incidence rate has been gradually increasing in recent years.Most patients have lost the opportunity for surgery at the time of diagnosis,and traditional systemic chemotherapy has limited efficacy.In recent years,significant progress has been made for targeted immunotherapy guided by the concept of the precise treatment of tumor.This article reviews the precise diagnosis and treatment of BTC and discusses its clinical application.
作者
范瑞林
丁宗仁
曾永毅
FAN Ruilin;DING Zongren;ZENG Yongyi(Mengchao Hepatobiliary Hospital of Fujian Medical University,Hepatobiliary Medical Center of Fujian Province,Fuzhou 350025,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2023年第9期2025-2030,共6页
Journal of Clinical Hepatology
基金
国家自然科学基金面上项目(62275050)
福建省科技创新联合资金项目(2019Y9108)
福建省卫健委中青年科研重大项目(2021ZQNZD013)。
关键词
胆道肿瘤
精准医学
诊断
治疗学
Biliary Tract Neoplasms
Precision Medicine
Diagnosis
Therapeutics