摘要
二尖瓣反流(MR)是最常见的心脏瓣膜疾病之一,经导管二尖瓣置换术(TMVR)逐步成为治疗MR的重要研究及发展方向。本文阐述了TMVR产品目前研发遇到的技术难点以及TMVR未来的发展趋势,对多款国内外TMVR产品设计特点进行比较分析,概括了TMVR产品设计开发时需要考虑的重点与难点,如锚定、瓣周漏、流出道梗阻等。最后对TMVR产品未来的市场前景进行了展望。
Mitral regurgitation(MR)is one of the most common heart valve diseases,and transcatheter mitral valve replacement has gradually become an important research and development direction for treating MR.This article elucidates the technical challenges encountered in the development of TMVR products and the future trends of TMVR.A comparative analysis of the design features of various domestic and international TMVR products is presented,summarizing the key considerations and challenges in the design and development of TMVR products,such as anchoring,paravalvular leakage,and outfl ow tract obstruction.Finally,the future market prospects of TMVR products are discussed.
作者
尚小珂
虞奇峰
杨洁琰
王雪丽
陈松
孙明
吴春林
张雄
王美莹
张长东
柳梅
董念国
SHANG Xiao-ke;YU Qi-feng;YANG Jie-yan;WANG Xue-li;CHEN Song;SUN Ming;WU Chun-lin;ZHANG Xiong;WANG Mei-ying;ZHANG Chang-dong;LIU Mei;DONG Nian-guo(Department of Cardiovascular Surgery,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)
出处
《中国介入心脏病学杂志》
CSCD
2023年第8期609-614,共6页
Chinese Journal of Interventional Cardiology
基金
“十三五”国家重点研发计划项目(2016YF0101100)
“十四五”国家重点研发计划项目(2021YF1101900)。
关键词
经导管二尖瓣置换术
二尖瓣反流
瓣周漏
瓣膜锚定
左心室流出道梗阻
Transcatheter mitral valve replacement
Mitral regurgitation
Paravalvular leakage
Valve anchoring
Left ventricular outflow tract obstruction