胸腔镜下肺癌根治术后mMRC分级与膈肌活动度相关性分析

Correlation Analysis between Postoperative mMRC Classification and Diaphragmatic Activity in Video-assisted Thoracoscopic Surgery for Lung Cancer

目的 探讨胸腔镜下肺癌根治术后患者mMRC分级与膈肌活动度之间的相关性,为肺癌手术后患者康复训练提供指导意见。方法 本研究纳入了50例肺癌根治术后患者。术后对患者进行mMRC分级和膈肌活动度超声测定。根据患者mMRC分级将其分为轻度呼吸障碍组(0-1级)和中度至重度呼吸障碍组(2-4级)。将膈肌活动度测定结果与患者mMRC分级进行统计分析。结果 在50例患者中,有17例患者属于轻度呼吸障碍组,33例患者属于中度至重度呼吸障碍组。轻度呼吸障碍组的患侧膈肌深呼吸活动度明显高于中重度呼吸障碍组的患者(P<0.05)。使用回归模型发现,mMRC分级随深呼吸时患侧膈肌活动度下降而上升趋势。结论 患侧深呼吸膈肌活动度与mMRC分级之间存在负的相关性,患侧深呼吸膈肌活动度具有预测术后呼吸功能障碍的可能。

Objective To investigate the relationship between mMRC grading and diaphragmatic activity in patients undergoing thoracoscopic radical resection of lung cancer and provide guidance for postoperative rehabilitation training for lung cancer patients.Methods This study enrolled 50 patients who underwent radical surgery for lung cancer.Postoperative mMRC grading and ultrasound measurement of diaphragm activity were performed.Based on mMRC grading,patients were divided into two groups:mild respiratory disorder group(grades 0-1)and moderate to severe respiratory disorder group(grades 2-4).Statistical analysis was conducted on the results of diaphragm activity measurement and mMRC grading.Results Among the 50 patients,17 belonged to the mild respiratory disorder group,while 33 belonged to the moderate to severe respiratory disorder group.The deep respiratory activity of the affected diaphragm was significantly higher in the mild respiratory disorder group compared to the moderate to severe respiratory disorder group(P<0.05).A linear regression model indicated that there was an upward trend in mMRC grading with a decrease in the activity of the affected diaphragm during deep breathing.There is a negative correlation between deep respiratory activity of the affected diaphragm and mMRC grading.Conclusion the deep respiratory activity of the affected diaphragm has the potential to predict postoperative respiratory dysfunction.These findings can contribute to the development of rehabilitation training protocols for lung cancer patients after surgery.