3种常见病原体在泉州地区男性泌尿生殖系统感染中的特点

Detection and analysis of three kinds of pathogen in the patients with urogenital system infection in Quanzhouarea

目的石研究沙眼衣原体(CT)、淋球菌(NG)、解脲脲原体(UU)在泉州地区男性泌尿生殖系统感染中的分布特点及尿沉渣结果特点。方法选择2015年3月至2020年7月在本院泌尿外科及皮肤性病科就诊的疑似泌尿生殖系统感染的1360例患者,按年龄将患者划分为15~19岁组(51例)、20~29岁组(625例)、30~39岁组(448例)、40~49岁组(171例)、≥50岁组(65例)。采用PCR法检测疑似泌尿生殖系统感染的生殖道分泌物中的CT、NG、UU,并分析患者尿沉渣结果与感染病原体类别间的相关性。结果CT和NG阳性检出率比较,差异无统计学意义(P>0.05),UU阳性检出率显著高于CT、NG,差异均有统计学意义(均P<0.05)。15~19岁组的CT阳性检出率显著高于≥50岁组(P<0.05),而NG阳性检出率显著高于所有其他组(均P<0.05)。20~29岁、30~39岁组的3种病原体总阳性检出率显著高于≥50岁组(均P<0.05)。15~19岁组的CT和NG混合感染高于20~29岁、30~39岁、40~49岁组(均P<0.05)。15~19岁组的NG和UU混合感染高于20~29岁组;15~19岁组的3种病原体混合感染高于30~39岁组(P<0.05)。尿潜血更多见于NG感染者。单一感染者(69例)和混合感染者(18例)的临床治愈时间比较,差异无统计学意义(P=0.134)。结论泉州地区泌尿生殖道感染具有年轻化趋势,处于性活跃期的20~39岁人群的总感染率最高;伴有NG感染患者的尿潜血指标更易出现异常。

Objective To study the distribution characteristics of chlamydia trachomatis(CT),neisseria gonorrhoeae(NG)and ureaplasma uuyticum(UU)in male urinary and reproductive system infection and the characteristics of urinary precipitation results in Quanzhou area.MethodssA total of 1360 patients with suspected genitourinary system infection were selected from the Department of Urology and Dermatology and venereal diseases of our hospital from March 2015 to July 2020.CT,NG and UU in genital tract secretions suspected of genitourinary system infection were detected by PCR method,and the correlation between urinary sediment results and types of infectious pathogens was analyzed.Results The difference in positive detection rates between CT and NG was not statistically significant(P>0.05),while the positive detection rate of UU was significantly higher than that of CT and NG,with statistical significance(all P<0.05).The CT positive detection rate in the 15-19 year old group was significantly higher than that in the≥50 year old group(P<0.05),while the NG positive detection rate was significantly higher than all other groups(all P<0.05).The total positive detection rates of three pathogens in the 20-29 year old and 30-39 year old groups were significantly higher than those in the≥50 year old group(all P<0.05).The mixed infection of CT and NG in the 15-19 year old group was higher than that in the 20-29 year old,30-39 year old,and 40-49 year old groups(all P<0.05).The mixed infection of NG and UU in the 15-19 year old group was higher than that in the 20-29 year old group;The mixed infection of three pathogens in the 15-19 year old group was higher than that in the 30-39 year old group(P<0.05).Urinary occult blood was more commonly seen in the NG isolated infection group(P<0.05).There was no statistically significant difference in clinical cure time between single infected individuals(69 cases)and mixed infected individuals(18 cases)(P=0.134).Conclusions In Quanzhou,urogenital tract infection tends to be younger,and the total infection rate of the sexually active 20-39 year old group is the highest.The urinary occult blood indexes of patients with NG infection are more likely to be abnormal,which should be paid attention to by clinicians.