肝硬化与衰弱的相关性研究进展

Research progress on the correlation between cirrhosis and frailty

衰弱预示着较高的依赖性和死亡率,是快速老龄化国家的医疗保健系统的一个主要挑战,越来越受到人们的关注。肝硬化常合并衰弱,衰弱是影响患者健康结局的重要因素。了解衰弱的危险因素、明确肝硬化合并衰弱的机制、及早识别和减缓衰弱的发生和发展对肝硬化患者预后有重要意义。现就肝硬化合并衰弱的研究现状进行综述,包括衰弱的定义和危险因素、肝硬化合并衰弱的机制、相关性及干预措施,旨在提高对肝硬化合并衰弱的认识,以期为加强肝硬化患者衰弱的早期识别、管理及干预提供帮助。

Frailty,which predicts high dependency and mortality,is a major challenge for healthcare systems in nations that are rapidly aging and is receiving increasing attention.Cirrhosis is often combined with frailty,which has a significant impact on patient health outcomes.Understanding the risk factors for frailty,elucidating the mechanism of cirrhosis combined with frailty,and early recognition and slowing down the occurrence and development of frailty are of great significance for the prognosis of cirrhotic patients.This article reviews the current research status of cirrhosis combined with frailty,including the definition and risk factors,mechanism,correlation,and intervention measures,in order to improve understanding and provide assistance for strengthening early identification,management,and intervention.