紫外线照射在疾病发生发展中的作用研究进展

Research progress on roles of ultraviolet irradiation in diseases

太阳中发出的电磁光谱包括可见光、红外光和紫外光(UV)。太阳光中的紫外光是研究的热点之一。过去的研究更多关注紫外光对皮肤的影响,因为紫外线是导致皮肤损伤的原因之一,人们对于紫外线对皮肤的生理效应已经比较清晰,但目前紫外线对于人体其他器官的影响以及对人类疾病的影响尚不明晰。本综述指出紫外线照射在减少体重增加、代谢功能障碍和心血管疾病方面有一定的益处。另外紫外线暴露可能在降低糖尿病、结肠炎等疾病的发病等方面有一定的帮助。且紫外线还可能在抑制近视和抑郁症的发展上发挥一定的作用。这给未来人类的疾病的治疗提供了新的思路,在后续的相关疾病的治疗中可以考虑紫外线因素;本文评述了紫外线暴露对于人类非皮肤类疾病的影响,探索到急性的紫外线暴露对于内脏可能会有损伤,而不只停留于皮肤层面,明晰了紫外线对人体的益处和危害,为探究紫外线深层次开发和控制紫外线剂量提供理论参考和研究方向。

The electromagnetic spectrum emitted by the sun includes visible light,infrared,and ultraviolet(UV).Among them,UV is one of the hotspots of research.Previous studies have paid more attention to the impact of UV on the skin because UV is one of the causes of skin damage.The physiological effects of UV on the skin are well understood,but its impacts on other organs of the body and other human diseases are unclear yet.This review pointed to the benefits of UV exposure in reducing weight gain,metabolic dysfunction,and cardiovascular disease.In addition,UV exposure may be helpful in reducing the incidence of diseases such as diabetes and colitis.UV may also play a role in inhibiting the development of myopia and depression.These findings provide new ideas for applying UV in the treatment of human diseases in the future.This paper reviewed the impacts of UV exposure on human non-skin diseases and explored the possibility of damage of acute UV exposure to organs,not only at the skin level,clarified the benefits and harms of UV for human body,and provided theoretical reference and research directions for deep UV exploitation and UV dose control.