8F Zelante和6F Solent血栓去除导管治疗下肢深静脉血栓形成的疗效对比分析

Comparison of single center efficacy analysis of 8F Zelante and 6F Solent thrombectomy catheter in the treatment of deep vein thrombosis of lower limbs

目的比较8F Zelante和6F Solent血栓去除导管治疗下肢深静脉血栓形成(DVT)的疗效。方法回顾性分析复旦大学附属中山医院厦门医院血管外科2020年6月至2022年12月收治的51例急性或亚急性DVT患者的临床资料, 其中男性22例, 年龄(60.5±14.4)岁。根据血栓去除导管不同, 分为Zelante组和Solent组。比较分析两组的溶栓时间、支架植入率、血栓清除率、通畅率、深静脉血栓后综合征(PTS)发生率和并发症等指标。结果 51例DVT患者中, Zelante组15例, Solent组36例。Zelante组术中吸栓时间[(322.7±78.1)s 比(416.4±61.5)s, t=4.577, P=0.001]和溶栓时间[(46.3±28.8)h 比(96.1±39.5)h, t=2.796, P=0.010]少于Solent组, 但总体血栓清除效果优于Solent组(χ2=7.913, P=0.019), 差异均具有统计学意义。两组支架植入率、单次住院滤器回收情况比较, 差异无统计学意义(P均>0.05)。51例患者均获得随访, 随访时间为(12.6±7.1)个月(范围:1~30个月)。随访期间, Zelante组无PTS出现。Solent组中再干预3例;PTS 6例, 其中3例为重度。结论相较6F Solent血栓去除导管, 8F Zelante导管治疗DVT具有更好的血栓清除效果, 并发症更少。

Objective To compare the efficacy of 8F Zelante and 6F Solent thrombectomy catheters in the treatment of deep vein thrombosis(DVT)of the lower extremities.Methods The clinical data of 51 patients with acute or subacute DVT admitted to the Department of Vascular Surgery,Xiamen Branch,Zhongshan Hospital,Fudan University from June 2020 to December 2022 were prospectively collected and retrospectively analyzed.Among them,there were 22 males,aged(60.5±14.4)years.They were divided into the Zelante group and the Solent group according to different catheters.The thrombolytic time,stent implantation rate,thrombus clearance rate,patency rate,the incidence of post-thrombotic syndrome(PTS),and complications in the two groups were compared.Results There were 15 cases in Zelante group and 36 cases in Solent group.The intraoperative thrombectomy time[(322.7±78.1)s vs.(416.4±61.5)s,t=4.577,P=0.001]and thrombolysis time[(46.3±28.8)h vs.(96.1±39.5)h,t=2.796,P=0.010]in the Zelante group were less than those in the Solent group.The overall thrombus clearance effect in the Zelante group was better than that in the Solent group(χ2=7.913,P=0.019),and the differences were statistically significant.In terms of stent implantation rate and retrieval rate for filters during a single hospital stay,there was no statistically significant difference between the two groups(both P>0.05).All 51 patients were followed up for(12.6±7.1)months(range:1-30 months).During the follow-up period,there was no PTS in the Zelante group,while in the Solent group,there were 3 cases of reintervention,and 6 cases of PTS,of which 3 cases were severe.Conclusion Compared with 6F Solent catheter,8F Zelante catheter has a better thrombus clearance effect and fewer complications in the treatment of DVT.