肌少-骨质疏松症的研究进展

Research progress on the osteosarcopenia

肌少-骨质疏松症是肌少症和骨质疏松症并存的老年疾病。随着人口老龄化, 肌少-骨质疏松症的发生率在今后几十年将大幅增加, 其不良后果包括更高的跌倒、骨折、虚弱和死亡风险。尽早对肌少-骨质疏松症进行诊断和干预治疗, 对于提高老年人生活质量具有重大意义。本文就肌少-骨质疏松症的诊断、分子机制、不良后果及可能的治疗方案进行综述。

Osteosarcopenia is a geriatric disease in which sarcopenia and osteoporosis coexist.With the aging,the incidence of osteosarcopenia will increase significantly in the next few decades,with adverse consequences including a higher risk of falls,fractures,weakness,and death.Early diagnosis and intervention of osteosarcopenia are of great significance in improving the quality of life of the elderly.This article reviews the diagnosis,molecular mechanisms,adverse consequences,and possible treatment options for osteosarcopenia.