针刺背俞穴联合耳穴压豆治疗糖尿病前期临床研究

Clinical Study on Acupuncture at Back-Shu Point Combined with Auricular Point Seed-Pressing for Prediabetes Mellitus

目的:观察针刺背俞穴联合耳穴压豆治疗糖尿病前期(PDM)脾虚湿盛证的临床疗效。方法:选择60例PDM脾虚湿盛证患者,采用随机数字表法分为干预组和对照组各30例。2组均给予健康宣教和生活方式干预,对照组给予耳穴压豆治疗,干预组在对照组基础上加用针刺背俞穴治疗,2组均治疗2个月。比较2组临床疗效、中医证候积分、血糖指标及胰岛功能指标。结果:治疗后,干预组临床疗效总有效率86.67%,高于对照组63.33%(P<0.05)。2组形体肥胖、腹部增大、倦怠乏力、纳呆便溏、口淡无味或口腻积分均较治疗前降低(P<0.05),干预组形体肥胖、腹部增大、倦怠乏力、纳呆便溏、口淡无味或口腻积分均低于对照组(P<0.05)。2组糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2 h血糖(P2hBG)水平均较治疗前降低(P<0.05),干预组HbA1c、FBG、P2hBG水平均低于对照组(P<0.05)。2组空腹胰岛素(FINS)、空腹C肽(FCP)水平及胰岛素敏感指数(ISI)、胰岛素抵抗指数(HOMA-IR)均较治疗前降低(P<0.05),干预组FINS、FCP水平及ISI、HOMA-IR均低于对照组(P<0.05)。结论:针刺背俞穴联合耳穴压豆治疗PDM脾虚湿盛证疗效较好,可缓解患者的临床症状,改善其血糖水平和胰岛功能。

Objective:To observe the clinical effect of acupuncture at back-shu point combined with auricular point seed-pressing for prediabetes mellitus(PDM)with spleen deficiency and damp exuberance syndrome.Methods:A total of 60 cases of PDM patients with spleen deficiency and damp exuberance syndrome were selected and divided into the intervention group and the control group according to the random number table method,with 30 cases in each group.Both groups were given health education and life style intervention;the control group was treated with auricular point seed-pressing,and the intervention group was additionally treated with acupuncture at back-shu point based on the treatment of the control group.Both groups were treated for 2 months.The clinical effects,traditional Chinese medicine syndrome scores,blood glucose indexes,and islet function indexes were compared between the two groups.Results:After treatment,the total clinical effective rate was 86.67%in the intervention group,higher than that of 63.33%in the control group(P<0.05).The scores of body obesity,abdominal enlargement,fatigue and hypodynamia,poor appetite and loose stool,and tastelessness or greasy mouth in the two groups were decreased when compared with those before treatment(P<0.05),and the scores of body obesity,abdominal enlargement,fatigue and hypodynamia,poor appetite and loose stool,and tastelessness or greasy mouth in the intervention group were lower than those in the control group(P<0.05).The levels of hemoglobin A1c(HbA1c),fasting blood glucose(FBG),and postprandial 2-hour blood glucose(P2hBG)in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of HbA1c,FBG,and P2hBG in the intervention group were lower than those in the control group(P<0.05).The levels of fasting insulin(FINS)and fasting C-peptide(FCP),insulin sensitivity index(ISI),and Homeostatic Model Assessment of Insulin Resistance(HOMA-IR)in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of FINS and FCP,ISI,and HOMA-IR in the intervention group were lower than those in the control group(P<0.05).Conclusion:Acupuncture at back-shu point combined with auricular point seed-pressing has a good curative effect in treating PDM with spleen deficiency and damp exuberance syndrome,which can alleviate the clinical symptoms of patients,and improve their blood glucose levels and islet function.