免疫型肠内营养支持对老年颅脑损伤患者营养状态及免疫球蛋白水平的影响

Effects of immune enteral nutrition support on nutritional status and immunoglobulin levels in elderly patients with craniocerebral injury

目的探讨免疫型肠内营养支持对老年颅脑损伤患者营养状态及免疫球蛋白水平的影响。方法选取2018年5月至2020年5月本院收治的60例老年颅脑损伤患者作为研究对象,按照随机数字表法分为两组,各30例。对照组采用常规肠内营养支持,观察组采用免疫型肠内营养支持,比较两组营养状态、免疫球蛋白水平及恢复时间。结果治疗7 d后,观察组血清总蛋白(TP)、转铁蛋白(TF)、白蛋白(ALB)水平均高于对照组,差异有统计学意义(P<0.05);治疗7 d后,观察组IgA、IgG、IgM水平均高于对照组,差异有统计学意义(P<0.05)。两组感染率比较差异无统计学意义;观察组肠道通气时间、住院时间、机械通气时间均短于对照组,差异有统计学意义(P<0.05)。结论免疫型肠内营养支持可进一步改善老年颅脑损伤患者营养状态,提升免疫球蛋白水平,降低并发症发生率。

Objective To investigate the effects of immune enteral nutrition support on nutritional status and immunoglobulin levels in elderly patients with craniocerebral injury.Methods 60 elderly patients with craniocerebral injury admitted to our hospital from May 2018 to May 2020 were selected as research subjects,and they were divided into two groups according to randomnumber table method,with 30 cases in each group.The control group received conventional enteral nutrition support,and the observation group received immune enteral nutrition support,the nutritional status,immunoglobulin level and recovery time were compared between the two groups.Results After 7 d of treatment,the levels of serum total protein(TP),transferrin(TF)and albumin(ALB)in the observation group were higher than those in control group,the differences were statistically significant(P<0.05).After 7 d of treatment,the levels of IgA,IgG and IgM in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).There was no significant difference in infection rate between the two groups;the intestinal ventilation time,hospitalization time and mechanical ventilation time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Immunotype enteral nutrition support can further improve the nutritional status of elderly patients with craniocerebral injury,increase the level of immunoglobulin,and reduce the incidence of complications.