海藻玉壶汤与结节性甲状腺肿相关因子表达影响的研究

Study on the Effect of Haizao Yuhu Decoction(海藻玉壶汤)on the Expression of Related Factors in Nodular Goiter

结节性甲状腺肿患者的患病率随着生活方式的改变及医疗检验条件的提高,逐渐的增多,因此针对此病的治疗尤为迫切。现代医学针对结节性甲状腺肿的治疗多采用手术、补碘等,易复发,且不良反应多,有的甚至需要终身服用药,对患者的生活造成长期的困扰。海藻玉壶汤作为中医治疗瘿病的代表方,历史悠久,疗效显著,通过检索近年数据库,发现其治疗结节性甲状腺肿与细胞凋亡的调节因子有关,但是复方与这些因子之间如何作用的还待进一步研究,方中含有海藻甘草反药组合,相反又相成的机制也需要进一步研究。

The prevalence of patients with nodular goiter increases gradually with the change of lifestyle and the improvement of medical examination conditions.Therefore,the treatment of this disease is particularly urgent.The treatment of nodular goiter in modern medicine mostly adopts surgery and iodine supplementation,which is easy to relapse and has great side effects.Some even need to take medicine for life,causing long-term trouble to the life of patients.Haizao Yuhu Decoction(海藻玉壶汤),as the representative prescription of traditional Chinese medicine in the treatment of gall disease,has hundreds of years of experience in the treatment of this disease and has remarkable curative effect.Through searching the database in recent years,it is found that its treatment of nodular goiter is related to the regulatory factors of apoptosis,but how the compound plays a role with these factors needs to be further studied.The prescription contains the anti drug combination of seaweed hay,and the opposite mechanism also needs to be further studied.