温针灸联合中药穴位敷贴对寒凝血瘀型痛经患者疼痛及炎症因子水平的影响

Effect of Warm Acupuncture and Moxibustion Combined with Acupoint Application of Traditional Chinese Medicine on Pain and the Levels of Inflammatory Factors in Patients with Dysmenorrhea of Cold Coagulation and Blood Stasis Type

目的:探讨温针灸联合中药穴位敷贴在寒凝血瘀型痛经患者中的应用价值,并观察其对疼痛及炎症因子水平的影响。方法:纳入2020年1月—2022年1月新余市人民医院收治的寒凝血瘀型痛经患者80例。按照随机数字表法将其分为观察组和对照组,各40例。对照组接受温针灸干预,观察组加用中药穴位敷贴。比较两组临床疗效、疼痛程度[视觉模拟评分法(VAS)]及炎症因子[白细胞介素-8(IL-8)、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)]。结果:干预3个月经周期后,观察组总有效率(95.00%)高于对照组(77.50%),差异有统计学意义(P<0.05)。干预3个月经周期后,两组VAS评分均低于干预前,且观察组低于对照组(P<0.05)。干预3个月经周期后,两组血清TNF-α、hs-CRP及IL-8指标较干预前均降低,且观察组各指标水平变化更显著(P<0.05)。结论:温针灸联合中药穴位敷贴对寒凝血瘀型痛经患者效果显著,可有效缓解患者疼痛,改善炎症因子。

Objective:To explore the application value of warm acupuncture and moxibustion combined with acupoint application of traditional Chinese medicine in patients with dysmenorrhea of cold coagulation and blood stasis type,and to observe its effect on pain and the levels of inflammatory factors.Method:A total of eighty patients with dysmenorrhea of cold coagulation and blood stasis type admitted to Xinyu People's Hospital from January 2020 to January 2022 were included.They were divided into the observation group and the control group according to random number table method,with 40 cases in each group.The control group received warm acupuncture and moxibustion intervention,and the observation group added acupoint application of traditional Chinese medicine.The clinical efficacy,pain degree[visual analogue scale(VAS)]and inflammatory factors[interleukin-8(IL-8),highsensitivity C reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α)]were compared between the two groups.Result:After 3 menstrual cycles of intervention,the total effective rate of the observation group(95.00%)was higher than that of the control group(77.50%),the difference was statistically significant(P<0.05).After 3 menstrual cycles of intervention,the VAS scores in the two groups were lower than those before intervention,and the VAS score of the observation group was lower than that of the control group(P<0.05).After 3 menstrual cycles of intervention,the indexes of the serum TNF-α,hs-CRP and IL-8 in the two groups were decreased compared with those before intervention,and the levels of each index in the observation group changed more significantly(P<0.05).Conclusion:Warm acupuncture and moxibustion combined with acupoint application of traditional Chinese medicine has a significant effect on dysmenorrhea patients of cold coagulation and blood stasis type,which can effectively relieve pain and improve inflammatory factors.