肢体肿胀持续监测的探索研究

An Exploratory Study On Continuous Monitoring of Limb Swelling

目的应用同轴打印技术制作柔性传感器实时监测肢体周径,为急性骨筋膜室综合征及下肢深静脉血栓高危人群或病程早期患者提供持续监测。方法采用高纯度镓铟合金和聚二甲基硅氧烷制作电缆,以STC89C52单片机作为主控芯片设计输出及报警装置,验证电缆拉伸度与电阻变化关系、拉伸度及电阻值与输出数值变化关系,并在气球和健康人中验证变化关系可信度。结果电缆拉伸度-电阻变化曲线连续,电阻随拉伸度增加而增高,不同厚度硅胶条拉伸200%时电阻测量值差异有统计学意义。连接输出设备后,输出值随电阻增高而增高。10Ω报警阈值下,同一电缆的拉伸度基本相同,不同电缆间差异有统计学意义。以气球膨胀和健康人肢体运动模拟肢体膨胀,多次重复实验显示器读数变化与周径变化趋势一致。结论应用同轴打印技术制作的柔性传感器可快速准确反映出受试者肢体周径的变化,有良好的应用前景,为相关疾病早期的诊断及监测提供思路。

Objective To produce flexible sensors with coaxial printing technology,achieve real-time monitoring of limb circumference and provide continuous monitoring for patients with acute myofascial compartment syndrome and lower extremity deep vein thrombosis in high-risk groups or in the early course of the disease.Methods High-purity gallium-indium alloy and polydimethylsiloxane were used to make cables,and STC89C52 micro-controller as the main control chip was used to design the output and alarm devices.The relationship between the tensile degree of the cable and the change in resistance was verified,and the relationship among the tensile degree,the resistance value and the change in the output value were also explored.We verifed the credibility of the result in the balloon and in the healthy people.Results The cable stretch degree-resistance change curve was continuous.The resistance increases with the increase of stretch degree,and the resistance measurement value was statistically significant when different thicknesses of silica gel strips were stretched by 200%.After connecting the output device,the output value increased with increasing resistance.Under the 10Ωalarm threshold,the stretch degree of the same cable was similar,and statistically significant among different cables.Limb expansion was similuated with balloon expansion and healthy human limb movement.Repeated experiments showed same trend of monitor reading changes with circumference changes.Conclusion The flexible sensor made by applying coaxial printing technology can quickly and accurately reflect the changes in the circumference of the subject’s limb,which has good application prospects and provides ideas for the early diagnosis and monitoring of related diseases.