临床药师为主导的药学服务对艾滋病病毒感染者/艾滋病患者的影响

The influence of clinical pharmacist-led pharmaceutical care on HIV infected/AIDS patients

目的:探讨临床药师为主导的药学服务干预对艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者的影响。方法:选取2021年5月1日—2021年10月31日确诊并开始接受抗病毒治疗的206例患者,随机分为观察组与对照组,每组103例。对照组患者进行常规治疗,观察组在常规治疗的基础上使用临床药师为主导的药学服务干预。比较两组患者的用药依从性以及CD4^(+)T淋巴细胞的增幅。结果:观察组的用药依从性评分高于对照组,差异有统计学意义(P<0.05);观察组CD4^(+)T淋巴细胞的增幅高于对照组,差异有统计学意义(P<0.05)。结论:采用临床药师为主导的药学服务干预能够明显提高HIV/AIDS患者的治疗依从性和CD4^(+)T淋巴细胞的增幅。

Objective:To explore the impact of pharmaceutical care intervention led by clinical pharmacists on AIDS/AIDS patients.Methods:All 206 patients who were diagnosed and started receiving antiviral treatment in our hospital from May 1,2021 to October 31,2021 were selected.They were paired and divided into an observation group and a control group randomly,with 103 patients in each group.The control group received routine treatment,while the observation group received pharmaceutical intervention led by clinical pharmacists on the basis of routine treatment.Compare the adherence to medication and the increase in CD4^(+)T lymphocytes between two groups of patients.Results:The medication compliance score of the observation group was significantly higher than that of the control group,and there was a significant difference between the data(P<0.05).There was a significant statistical difference(P<0.05)in the increase of CD4^(+)T lymphocytes between the observation group and the control group that provided pharmaceutical services.Conclusion:The use of clinical pharmacist led pharmaceutical service interventions for HIV/AIDS patients can significantly improve their treatment compliance.