基于镜像疗法的脑机接口技术在脑卒中患者上肢功能康复中的应用

Application of mirror-therapy combined with brain-computer interface technology in upper limb functional rehabilitation of patients after stroke

目的 探讨基于镜像疗法的脑机接口(BCI)技术在脑卒中患者上肢功能康复中的应用效果,为脑卒中患者的康复治疗提供依据。方法 选择2021年1-10月在徐州市中心医院住院的脑卒中上肢功能障碍患者25例,所有患者均达到强制性运动治疗的标准,采用随机数字表法将患者分为观察组(13例)和对照组(12例),对照组采取常规康复治疗,观察组在常规康复治疗的基础上采用基于镜像疗法的BCI技术进行干预。在8周的康复治疗过程中,观察组退出1例,对照组退出2例。比较两组患者治疗后上肢Fugl-Meyer运动功能评定量表(FMA)、蒙特利尔认知评估量表(MoCA)、健康调查简表(SF-36)评分和改良Barthel指数。结果 治疗前,两组上肢FMA、MoCA、SF-36评分及改良Barthel指数比较,差异均无统计学意义(P>0.05)。治疗后,观察组上肢FMA、MoCA、SF-36评分及改良Barthel指数均明显高于治疗前(P<0.05),对照组上肢FMA、SF-36评分均明显高于治疗前(P<0.05),但MoCA评分和改良Barthel指数治疗前后无明显差异(P>0.05)。两组间比较结果显示:治疗后,观察组上肢FMA、MoCA、SF-36评分及改良Barthel指数均高于对照组,差异有统计学意义(P<0.05)。结论 基于镜像疗法的BCI技术在脑卒中上肢功能障碍患者中的应用能有效改善患者的上肢功能,促进患者认知能力和生活质量的提高。

Objective To explore the application effect of mirror-therapy combined with brain-computer interface(BCI)technology in upper limb function rehabilitation of patients after stroke,and to provide basis for rehabilitation treatment of stroke patients.Methods A total of 25 stroke patients with upper limb dysfunction who were hospitalized in Xuzhou Central Hospital from January to October 2021 were selected,all of whom met the criteria for mandatory exercise therapy.The patients were divided into the observation group(13 cases)and control group(12 cases)using the table of random numbers.The control group received routine rehabilitation treatment,and the mirror-therapy combined with BCI technology was applied on the basis of routine rehabilitation treatment in the observation group.During the 8-week rehabilitation treatment,one case was withdrawn from the observation group,and two cases were withdrawn from the control group.The scores of upper limb Fugl-Meyer assessment(FMA),Montreal cognitive assessment(MoCA),short-form 36 health survey scale(SF-36)and modified Barthel index were compared between the two groups after treatment.Results Before treatment,there was no significant difference in upper limb FMA,MoCA,SF-36 scores and modified Barthel index between the two groups(P>0.05).After t reatment,the upper limb FMA,MoCA,SF-36 scores and modified Barthel index in the observation group were significantly higher than those before treatment(P<0.05),and the upper limb FMA and SF-36 scores in the control group were significantly higher than those before treatment(P<0.05),but there was no significant difference in MoCA score and modified Barthel index between before and after treatment(P>0.05).The results of comparison between the two groups showed that after treatment,the FMA,MoCA,SF-36 scores and modified Barthel index of upper limb in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The application of mirror-therapy combined with BCI technology in stroke patients with upper limb dysfunction can effectively improve the upper limb function of patients,and promote the improvement of patients’cognitive ability and quality of life.