二氧化碳激光联合白细胞介素-2治疗女性尖锐湿疣

CO_2 laser combined with interleukin-2 in treatment of female condyloma acuminatum

目的 :研究CO2 激光联合白细胞介素 2(IL 2 )治疗女性尖锐湿疣的疗效及比较 3种方法的效果。方法 :80例女性尖锐湿疣病人分为 3组。CO2 激光组 ,仅用CO2 激光治疗 ;CO2 激光 +IL 2肌注组 ,CO2 激光后再予IL 2 ,2 0万U ,im ,qod× 10次 ;CO2 激光 +IL 2皮损下注射组 ,CO2 激光后再予IL 2 ,2 0万U ,皮损下注射 qod× 10次。结果 :CO2激光 +IL 2皮损下注射组 ,CO2 激光 +IL 2肌注组和CO2 激光组的总有效率分别为 90 % ,6 3%和33%。P <0 .0 1。结论 :CO2 激光 +IL 2治疗女性尖锐湿疣有效 ,但IL

AIM: To study the clinical efficacy of CO 2 laser combined with interleukin-2(IL-2) in treatment of female condyloma acuminatum(CA). METHODS: Eighty female patients with CA were divided into 3 groups. Patients in CO 2 laser group were treated with CO 2 laser only; patients in group of CO 2 laser+IL-2 muscle injection were treated with CO 2 laser and IL-2200 kU, im, qod×10 times; patients in group of CO 2 laser+IL 2 sub-lesional injection were treated with CO 2 laser and IL-2 200 kU, sub-lesional inj, qod×10 times. RESULTS: The total clinical effective rates were 33 % for CO 2 laser group, 63 % for CO 2 laser+IL-2 muscle injection group, 90 % for CO 2 laser+IL-2 sub-lesional injection group(P<0.01). CONCLUSION: CO 2 laser+IL-2 is effective for female CA, and IL-2 sub-lesional injection is more effective.