乙基香兰素/环糊精包合物制备及表征

Preparation and Characterization of EVA/CDs Inclusion

乙基香兰素是应用非常广泛的食品添加剂香料,其疏水性限制了生物利用度。本研究采用计算机辅助设计模拟了乙基香兰素与四种环糊精形成包合物,进一步采用溶剂蒸发法制备了乙基香兰素/环糊精包合物,并以UV-Vis、FT-IR、XRD、RSC等进行表征,结果表明,EVA与HP-β-CDs具有最高稳定常数,具有良好溶解性。

Ethyl vanillin(EVA)as a kind of flavor is widely used in food industry,but low solubility restricted its application.This study using computer-aided design simulated interaction between EVA and four kinds of computeraided design computer-aided design cyclodextrins(CDs)and further fabricated their inclusions.Results shown that EVA/HP-β-CDs has better stability constant compared withα-CDs,β-CD andγ-CDs and solubility as well as non-crystal composites confirmed by UV-vis,XRD,FT-IR and RSC analysis.