老年吸入性肺炎患者预后的影响因素

Influencing factors of prognosis in elderly patients with aspiration pneumonia

目的:分析老年吸入性肺炎(AP)患者预后的影响因素。方法:选取2022年9月至2023年3月该院收治的150例老年AP患者进行横断面研究,收集其一般资料,观察其预后不良发生率,比较不同预后患者一般资料,采用多因素Logistic回归分析老年AP患者预后的影响因素。结果:150例老年AP患者预后不良41例,占27.33%(41/150)。预后不良患者急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分、血清超敏C反应蛋白(hs-CRP)水平、血清血管生成素-2(Ang-2)水平均高于预后良好患者,差异有统计学意义(P<0.05);不同预后患者的性别、年龄、体质量指数、糖尿病占比、高血压占比、心脑血管疾病占比、帕金森病占比、鼻饲占比、淋巴细胞计数、中性粒细胞比例、血红蛋白水平、总胆固醇水平、三酰甘油水平、空腹血糖水平、平均动脉压比较,差异无统计学意义(P>0.05)。多因素Logistic回归分析结果显示,APACHEⅡ评分>17.15分、血清hs-CRP>54.13 mg/L、血清Ang-2>12.33μmol/L均为老年AP患者预后不良的危险因素(OR>1,P<0.05)。结论:APACHEⅡ评分>17.15分、血清hs-CRP>54.13 mg/L、血清Ang-2>12.33μmol/L均为老年AP患者预后不良的危险因素。

Objective:To analyze influencing factors of prognosis in elderly patients with aspiration pneumonia(AP).Methods:A cross-sectional study was conducted on 150 elderly patients with AP admitted to the hospital from September 2022 to March 2023.Their general information was collected.The incidence of poor prognosis was observed.The general data of these patients with different prognosis were compared.Multivariate Logistic regression analysis was used to analyze the influencing factors of prognosis in the elderly patients with AP.Results:Among the 150 elderly AP patients,41 had poor prognosis,accounting for 27.33%(41/150).The acute physiology and chronic health status scoring system II(APACHE II)scores,the serum hypersensitive C-reactive protein(hs-CRP)levels,and the serum angiopoietin-2(Ang-2)levels of the patients with poor prognosis were higher than those of the patients with good prognosis,and the differences were statistically significant(P<0.05).There were no significant differences in gender,age,body mass index,proportion of diabetes,proportion of hypertension,proportion of cardiovascular and cerebrovascular diseases,proportion of Parkinson’s disease,proportion of nasal feeding,lymphocyte count,proportion of neutrophils,hemoglobin level,total cholesterol level,triacylglycerol level,fasting blood glucose level and mean arterial pressure among the patients with different prognosis(P>0.05).The multivariate logistic regression analysis showed that APACHE II score>17.15,serum hs-CRP>54.13 mg/L,and serum Ang-2>12.33μmol/L were all risk factors for poor prognosis in the elderly AP patients(OR>1,P<0.05).Conclusions:APACHE II score>17.15,serum hs-CRP>54.13 mg/L,serum Ang-2>12.33μmol/L are the risk factors of poor prognosis in the elderly AP patients.