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血清降钙素原/白蛋白比值在终末期肾病血液透析患者导管相关性感染中的预测价值

Predictive value of PCT/ALB value in catheter-related infection of hemodialysis patients with end-stage renal disease
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摘要 目的:分析降钙素原(PCT)/白蛋白(ALB)比值在终末期肾病血液透析患者导管相关性感染中的预测价值。方法:选取2019年6月至2021年5月该院收治的137例终末期肾病患者为观察组,另选取同期该院137名健康体检者137名为对照组。检测两组血清PCT、ALB水平,并计算PCT/ALB比值,统计终末期肾病患者导管相关性感染发生情况,采用受试者工作特征曲线(ROC)分析PCT/ALB比值在终末期肾病血液透析患者导管相关性感染中的预测价值。结果:137例终末期肾病血液透析患者发生导管相关性感染24例,占17.52%(24/137);观察组血清PCT水平和PCT/ALB比值均高于对照组,血清ALB水平低于对照组,差异有统计学意义(P<0.05);导管相关性感染患者血清PCT水平和PCT/ALB比值均高于未感染患者,血清ALB水平低于未感染患者,差异有统计学意义(P<0.05);ROC曲线分析结果显示,血清PCT、ALB、PCT/ALB比值预测终末期肾病血液透析患者导管相关性感染的曲线下面积分别为0.782、0.763、0.855,均有一定的预测价值,其中PCT/ALB比值的预测价值最高(P<0.05)。结论:PCT/ALB比值在终末期肾病血液透析患者导管相关性感染中的预测价值高于血清PCT、ALB水平。 Objective:To analyze predictive value of procalcitonin/albumin(PCT/ALB)value in catheter-related infection of hemodialysis patients with end-stage renal disease.Methods:137 patients with end-stage renal disease admitted to the hospital from June 2019 to May 2021 were selected as observation group,and 137 healthy subjects in the hospital during the same period were selected as control group.The serum PCT and ALB levels of the two groups were detected,and the PCT/ALB value was calculated.The occurrence of catheter-related infections in these patients with end-stage renal disease was assessed.The receiver operating characteristic curve(ROC)was used to analyze the predictive value of PCT/ALB value in catheter-related infection in the hemodialysis patients with end-stage renal disease.Results:There were 24 cases of catheter-related infection in the 137 hemodialysis patients with end-stage renal disease,accounting for 17.52%(24/137).The serum PCT level and the PCT/ALB value of the observation group were higher than those of the control group,the serum ALB level was lower than that of the control group,and the differences were statistically significant(P<0.05).The serum PCT level and the PCT/ALB value of the patients with catheter-related infection were higher than those of the patients without infection,the serum ALB level was lower than that of the patients without infection,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under curve(AUC)s of serum PCT,ALB and PCT/ALB in the prediction of catheter-related infection in the hemodialysis patients with end-stage renal disease were 0.782,0.763 and 0.855,separately,all of which had certain predictive value,among which PCT/ALB had the highest predictive value(P<0.05).Conclusions:The value of PCT/ALB in the prediction of catheter-related infection in the hemodialysis patients with end-stage renal disease is higher than that of serum PCT and ALB.
作者 周峰 ZHOU Feng(Department of Nephrology of Nanyang Hospital of Traditional Chinese Medicine,Nanyang 473000 Henan,China)
出处 《中国民康医学》 2023年第18期146-148,共3页 Medical Journal of Chinese People’s Health
关键词 终末期肾病 血液透析 导管相关性感染 降钙素原 白蛋白 预测 End-stage renal disease Hemodialysis Catheter-related infection Procalcitonin Albumin Prediction
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