滋水涵木法治疗围绝经期骨质疏松症临床观察

Clinical Observation of Nourishing Water to Moisten Wood Method in the Treatment of Perimenopausal Osteoporosis

目的:观察滋水涵木法治疗围绝经期骨质疏松症的临床疗效。方法:60例随机分为治疗组和对照组各30例,除去脱落病例(治疗组2例,对照组1例),实际完成病例总数57例,其中治疗组28例,对照组29例。治疗组28例给予健骨汤,对照组29例给予仙灵骨葆胶囊。结果:两组治疗后E_2水平均上升(P<0.05)。两组治疗后FSH水平均有不同程度下降,治疗组FSH水平与治疗前比较差异有统计学意义(P<0.05)。治疗后两组E_2水平比较差异有统计学意义(P<0.05),FSH水平比较差异无统计学意义(P>0.05)。治疗后两组血清Ca、P、ALP指标均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。结论:健骨汤治疗围绝经期骨质疏松症肝肾阴虚型疗效良好。

Objective:To observe the clinical effect of nourishing water to moisten wood method in the treatment of perimenopausal osteoporosis.Methods:Sixty cases were randomly divided into treatment group and control group,30 cases in each group.Excluding the drop-out cases(2 cases in the treatment group and 1 case in the control group),57 cases were actually completed,including 28 cases in the treatment group and 29 cases in the control group.Twenty-eight cases in the treatment group were given Jiangu Decoction,while twenty-nine cases in the control group were given Xianling Gubao Capsule.Results:The levels of E2 in the two groups increased afer treatment(P<0.05).After treatment,the FSH levels of the two groups decreased at diferent degree,and the FSH level of the treatment group was significantly different from that before treatment(P<0.05).After treatment,there was significant difference in E2 level between the two groups(P<0.05),but there was no significant difference in FSH level between the two groups(P>0.05).After treatment,the serum Ca,P and ALP indexes of the two groups were improved(P<0.05),and the improvement of the treatment group was better than that of the control group(P<0.05).Conclusion:Jiangu Decoction is effective in treating perimenopausal osteoporosis of liver-kidney yin deficiency type.