虾青素运载体系的研究进展

Research Progress in Delivery Systems for Astaxanthin

虾青素作为一种天然强抗氧化剂,不仅具有强抗氧化功效,还具有降血糖、抗炎、抗癌等生物功效。目前国内外均有生产虾青素的公司,且它们的产品广泛应用于水产饲料、保健品、医药等领域,这些行业对原材料的要求颇高,但虾青素存在水溶性低、稳定性差、合成成本高等问题,严重影响其产业应用。因此探究运用包埋技术保藏虾青素成为目前的研究热点,多种运载体系已被证明可以提高虾青素的稳定性和生物利用度。该综述回顾了基于虾青素运载体系的最新进展,并以脂质体、微胶囊、乳液为代表进行阐述。通过比较三种运载体系的包埋率、生物利用度、优缺点等方面,以期为虾青素的运载体系研究与应用提供参考,为虾青素市场应用提供科学依据。

Astaxanthin is a powerful antioxidant with a wide array of biological efficacies,such as strong antioxidant properties and blood-sugar-lowering,anti-inflammatory,and anti-cancer properties.Many companies produce and extract astaxanthin locally and abroad.Their products are widely used in aquatic feed,healthcare products,and pharmaceutical industries,which have high requirements for raw materials.However,astaxanthin has low water solubility,poor stability,and high extraction and synthesis costs,which considerably affect its industrial application.Therefore,exploring embedding technology for astaxanthin preservation is gaining considerable research attention.Several types of astaxanthin delivery systems have been shown to improve the stability and bioavailability of astaxanthin.Here,recent advances in astaxanthin delivery systems based on liposomes,microcapsules,and emulsions-based methods are reviewed and discussed.Comparisons of the encapsulation efficiency,bioaccessibility,and advantages and disadvantages of these three delivery systems are expected to provide a reference for research and application of astaxanthin delivery systems and establish a solid scientific foundation for the commercial application of astaxanthin.