ACBT对帕金森病患者呼吸及运动功能的影响

Effect of ACBT on respiratory and motor functions in patients with Parkinson's disease

目的探讨主动呼吸循环技术(ACBT)对帕金森病患者呼吸功能及运动功能的影响,以期为临床治疗提供参考。方法本研究选取2021年6月—2022年5月郑州市中心医院收治的64例原发性帕金森病患者为研究对象。采用随机数字表法将患者分为对照组与观察组,每组32例。对照组患者采用常规康复训练法进行干预,观察组患者在常规康复训练的基础上应用ACBT进行干预。比较2组患者干预前、干预后2周及干预后8周用力肺活量(FVC)、第一秒用力呼气容积(FEV_(1))、50%肺活量时的最大呼气流速(MEF_(50))等肺功能指标。比较2组患者干预前、干预后2周及干预后8周帕金森病综合评估量表(UPDRS)Ⅲ评分。比较2组患者干预前后(干预后为干预2周时)健康调查简表(SF-36)评分。结果干预前,2组患者FVC、FEV_(1)、MEF50比较,差异无统计学意义(P>0.05)。干预后2周、干预后8周,2组患者FVC、FEV_(1)及MEF50均大于干预前,差异均有统计学意义(P<0.05)。同时,干预后8周,观察组患者FVC、FEV_(1)、MEF50均大于对照组,差异均有统计学意义(P<0.05)。干预前及干预后2周,2组患者UPDRSⅢ评分比较,差异无统计学意义(P>0.05)。干预后8周,2组患者UPDRSⅢ评分均低于干预前,且观察组低于对照组,差异均有统计学意义(P<0.05)。干预前,2组患者SF-36中生理功能、精神健康、情感职能及总体健康评分比较,差异无统计学意义(P>0.05)。干预后,2组患者SF-36中生理功能、精神健康、情感职能及总体健康评分均高于干预前,且观察组高于对照组,差异均有统计学意义(P<0.05)。结论ACBT能较好地改善帕金森病患者的呼吸功能及运动功能,同时提高患者生活质量,且方法简单,患者依从性较高,值得临床推广应用。

Objective This paper aims to investigate the effect of active respiratory circulation technique(ACBT)on respiratory and motor functions in patients with Parkinson's disease(PD).Methods Sixty-four patients with primary Parkinson's disease admitted to Zhengzhou Central Hospital from June 2021 to May 2022 were selected as the study participants.They were randomly assigned to the control and observation groups,with 32 cases in each group.Patients in the control group received conventional rehabilitation training,and patients in the observation group,ACBT based on routine rehabilitation training.Forced vital capacity(FVC),forced expiratory volume in 1 second(FEV_(1)),maximal expiratory flow at 50%of vital capacity(MEF50)and other pulmonary function parameters were compared between the two groups before intervention,2 weeks after intervention and 8 weeks after intervention.The scores of Unified Parkinson's Disease Rating ScaleⅢ(UPDRSⅢ)were compared between the groups before intervention,2 weeks after intervention and 8 weeks after intervention.The 36-Item Short-Form Health Survey(SF-36)scores were compared between the groups before and after intervention(at 2 weeks after intervention).Results Before intervention,there was no significant difference in FVC,FEV_(1)and MEF_(50)between the two groups(P>0.05).At 2 weeks and 8 weeks after intervention,FVC,FEV_(1)and MEF_(50)in the two groups were significantly increased(P<0.05).Meanwhile,FVC,FEV_(1),and MEF_(50)in the observation group eight weeks after the intervention were significantly greater than those in the control group(P<0.05).No significant difference was observed in UPDRSⅢscores two weeks after intervention at the pre-intervention level between the two groups(P>0.05).Eight weeks after intervention,the UPDRSⅢscores of patients in both groups declined,and the observation group was lower than the control group,with statistical significance(P<0.05).Before intervention,there was no significant difference in physical functioning,mental health,role emotional and general health subscale scores in SF-36 between the two groups(P>0.05).After intervention,the physical functioning,mental health,role emotional and general health subscale scores in SF-36 in the two groups were increased,and the observation group was higher than the control group,with statistical significance(P<0.05).Conclusion ACBT can improve the respiratory and motor functions of patients with Parkinson's disease and raise their quality of life.The method is simple and the compliance is high.These benefits hold promise for a wider application of this technique clinically.