儿童呼吸道合胞病毒感染的免疫学研究进展

Advances in immunology of respiratory syncytial virus infection in children

呼吸道合胞病毒(RSV)是导致婴幼儿下呼吸道感染的常见病原体之一,可对婴幼儿肺部发育造成长期影响并引发严重并发症。该病毒已经成为儿童下呼吸道感染、死亡以及产生经济负担的重要因素之一。RSV感染引起的毛细支气管炎涉及复杂的免疫学过程,分析总结RSV感染的临床特点和患儿的免疫状态,能够及早识别高危人群并采取有效预防措施以降低其感染风险。本文就RSV感染的免疫学研究进展进行综述,旨在为RSV感染的诊治提供思路,减轻RSV相关问题所产生的经济负担。

Respiratory syncytial virus(RSV)is one of the most common pathogens causing lower respiratory tract infection in infants,which can lead to long-term effects on lung development and serious complications.The virus has become an important factor of lower respiratory tract infection,death and economical burden in children.Bronchiolitis caused by RSV infection involves a complex immunological process.Analysis and summary of the clinical characteristics of RSV infection and immune status of children can identify high-risk groups early and take effective preventive measures to reduce the risk of infection.This article reviews the advances in immunology of RSV infection to provide diagnosis and treatment ideas and reduce the economical burden caused by RSV-related problems.