熊果苷抗肿瘤潜能的研究进展

Research Progress on Distribution and AntitumorEffect of Arbutin in Plants

熊果苷是一种对苯二酚类葡萄糖苷,主要存在于菊科、杜鹃花科、山龙眼科科和蔷薇科植物中。熊果苷是目前应用最广泛的天然皮肤美白剂之一,除此之外,还具有其他与治疗相关的生物学特性,如抗氧化、抗炎以及抗癌的作用,研究表明熊果苷对膀胱癌、脑癌、乳腺癌等具有潜在的抗肿瘤特性,且具有较低的急性或慢性细胞毒性。本文综述了熊果苷抗各种癌症的研究进展,极大的增加了其成为天然抗癌药物的治疗潜力。

Arbutin is a kind of hydroquinone glucoside,which mainly exists in Asteraceae,Ericaceae,Proteaceae and Rosaceae families.Arbutin is one of the most widely used natural skin lighteners,in addition,has other treatment-related biological properties such as antioxidant,anti-inflammatory and anticancer effects.Studies have shown that arbutin has potential anti-tumor properties for bladder cancer,brain cancer,breast cancer,and has low acute or chronic cytotoxicity.The research progress on arbutin against various cancers was reviewed,which greatly increased its therapeutic potential as a natural anticancer drug.