生产和流通环节水产品中喹诺酮类抗生素污染特征及健康风险评估研究

Occurrence and Health Risk Assessment of QuinoloneAntibiotics in Aquatic Products during Production and Circulation

以养殖水产品为分析对象,采用超高液相色谱-串联质谱法对2019年某省生产和流通环节的38个品种685批次水产品中6种喹诺酮类抗生素(QNs)含量进行定量检测,同时评估居民摄入水产品中恩诺沙星的健康风险。结果显示,20.73%的水产品存在不同程度的QNs检出,不合格样品占2.34%,洛美沙星与培氟沙星均为未检出,其余4种QNs检出率为0.44%~16.64%。总体上检出浓度,蛙类>淡水鱼>龟鳖类>海水鱼>虾类>蟹类。检出的水产品以恩诺沙星、环丙沙星为主。水产品中恩诺沙星的健康风险处于较低水平,但应密切关注长期或大量食用蛙类、龟鳖类带来的健康风险。

The occurrence of quinolone antibiotics in aquiculture products(685 samples of 38 species)collected from production and circulation in 2019 were studied by ultra-high liquid chromatography-tandem mass spectrometry,and their health riskwas evaluated,simultaneously.The results showed that QNs were detected in 20.73%of aquatic,and 2.34%were unqualified samples.Lomefloxacin and pefloxacin were not detected,and the detection rates of the other four QNs ranged from 0.44%to 16.64%.In general,the concentrations of quinolone antibiotics were in the order of frogs>freshwater fish>turtles>seawater fish>shrimp>crabs.Enrofloxacin and ciprofloxacin were the predominant among the detected aquatic products.Based on health risk assessment,all detected aquatic products were considered safe for consumption,but the health risk caused by long-term or large amount consummation of frogs and turtles would require close attention.