视盘大小对视网膜神经纤维层和神经节细胞复合体厚度的影响

Effect of optic disc size on thickness of retinal nerve fiber layer and ganglion cell complex

视网膜神经纤维层(retinal nerve fiber layer,RNFL)与神经节细胞复合体(ganglion cell complex,GCC)测量已被广泛用于青光眼的筛查和早期诊断。但RNFL和GCC厚度受种族、年龄、性别、眼部因素及全身系统疾病等多种因素的影响。采用OCT对不同大小视盘的患者进行RNFL和GCC厚度测量时,视盘大小是其重要的影响因素之一。OCT常规扫描模式对RNFL进行测量时受到视盘大小的影响,视盘越大,所测得的RNFL越厚。因此比例扫描模式更适合用于不同类型视盘的RNFL测量。而与小视盘相比,大视盘患者是否具有更大的GCC测量值目前仍存在争议,需进一步研究验证。

Examination of retinal nerve fiber layer(RNFL)and ganglion cell complex(GCC)have been widely used for the screening and diagnosis of early glaucoma,but the thicknesses of RNFL and GCC are affected by race,age,sex,ocular factors and systemic diseases.Optic disc size is one of the important influencing factors for measuring the thickness of RNFL and GCC in patients with different optic disc sizes using optical coherence tomography(OCT).The measurement of RNFL in the normal scanning mode of OCT is influenced by the size of optic disc,and the RNFL in large optic disc is thicker.Therefore,proportional scanning mode is more suitable for RNFL measurement of different types of optic disc.However,it is still controversial whether patients with larger optic disc have greater GCC thickness measurements than those with small optic disc,which needs further study to verify.