从“和为圣度”探讨代谢相关脂肪性肝病辨治

Differentiation and Treatment of Metabolism Associated Fatty Liver Disease from“Harmony as the Supreme Principle”

通过对中医“和为圣度”内涵及代谢相关脂肪性肝病(MAFLD)因机证治进行分析,阐释在中医哲学思维指导下,“和为圣度”对该病临床辨证及治疗上的指导意义。“和为圣度”意指通过调和阴阳、升降、虚实等对峙、斗争的病机矛盾关系以纠正偏倚,达到人体阴阳、脏腑气血归于和谐的状态。立足“和为圣度”思维,以阴阳变化之规律为线索,将MAFLD病因分为阴阳两端,从阴阳盛衰探讨其病机演变,治疗则从阴阳和合入手,损其有余、补其不足,以达气血畅通而复肝脾生化之态。

Through analyzing the connotation of“Harmony as the Supreme Principle”in traditional Chinese medicine,etiology and pathogenesis,differentiation and treatment of metabolic associated fatty liver disease(MAFLD),this article explains the guiding significance of“Harmony as the Supreme Principle”in the clinical syndrome differentiation and treatment of this disease under the guidance of philosophical thinking of traditional Chinese medicine.The concept of“Harmony as the Supreme Principle”refers to correcting bias by reconciling the conflicting relationships between yin and yang,ascending and descending,deficiency and excess,in order to achieve a state of harmony between the body’s yin and yang,visceral qi and blood.Based on the thinking of“Harmony as the Supreme Principle”and using the law of changes in yin and yang as a clue,the etiology of MAFLD is divided into two ends:yin and yang.The evolution of its pathogenesis is explored from the rise and fall of yin and yang,and the treatment starts with the combination of yin and yang,damaging its surplus and supplementing its deficiency,in order to achieve the smooth flow of qi and blood and restore the normal state of the liver and spleen.