肌骨超声对RA患者腕关节活动性病情评估的临床价值

Clinical value of musculoskeletal ultrasound in assessing wrist joint disease activity in RA patients

目的:探究肌骨超声(MSUS)评估类风湿关节炎(RA)患者腕关节病情活动性的价值。方法:将2020年1月至2023年1月接受治疗的61例腕关节RA患者,根据病情活动性评分28(DAS28)评分分为活动期组(33例,DAS28评分≥2.6分)和缓解期组(28例,DAS28评分<2.6分),分析两组MSUS检查与血液学检测指标,MSUS总评分与DAS28评分的相关性。结果:活动期组MSUS总评分、抗环瓜氨酸肽抗体(抗CCP抗体)水平、类风湿因子(RF)水平、红细胞沉降率(ESR)均高于缓解期组,差异均有统计学意义(P<0.05);MSUS总评分与DAS28评分、抗CCP抗体、RF、ESR均呈正相关(P<0.05)。结论:MSUS可用于RA患者腕关节病情的评估与治疗效果评价。

Objective:To investigate the clinical value of musculoskeletal ultrasonography(MSUS)in assessing the activity of the wrist joint disease in patients with rheumatoid arthritis(RA).Methods:61 RA patients treated in our hospital from January 2020 to January 2023 were included in this study,who were divided into the active stage group(33 cases,DAS28 score≥2.6)and remission stage group(28 cases,DAS28 score<2.6)according to the disease activity score 28(DSA28).Then,MSUS examination and blood index detection were performed on all patients,and the correlation between the total MSUS score and hematological indexes were compared between the two groups.Results:The total score of MSUS,levels of anti-cyclic citrullinated peptide antibody(anti-CCP antibody),rheumatoid factor(RF)and erythrocyte deposition rate(ESR)in the active stage group were higher than those in remission stage group,which were of statistical differences(P<0.05);the total score of MSUS was positively correlated with DAS28 score,anti-CCP antibody,RF and ESR(P<0.05).Conclusion:MSUS can be used to evaluate the wrist activity and therapeutic effect in patients with RA.