自主功能性甲状腺结节的诊断与^(131)I治疗进展

Advances in diagnosis and ^(131)I therapy of autonomously functioning thyroid nodule

自主功能性甲状腺结节(AFTN)是一种能引起甲状腺毒症的疾病,结节可单发也可多发,其中99%为良性,多发生在甲状腺的2个侧叶,峡部少见。AFTN的治疗方法有手术、^(131)I治疗、抗甲状腺药物治疗、射频消融治疗等。其中^(131)I治疗是一种治疗AFTN的有效方法。笔者结合国内外文献报道,对AFTN的发病机制与诊断方法,以及^(131)I治疗的原理、临床应用与疗效等作一综述,为AFTN的临床诊疗提供参考。

Autonomously functioning thyroid nodule(AFTN)is a disease that can cause thyrotoxicosis.Nodules can be solitary or multiple,with 99%of them being benign and occurring mostly in the two lateral lobes of the thyroid gland.The isthmus is rare.The treatment methods for AFTN include surgery,^(131)I therapy,antithyroid drug,and radiofrequency ablation.^(131)I therapy is an effective treatment for AFTN.Based on domestic and foreign literature reports,the authors review the pathogenesis and diagnosis of AFTN,as well as the principle,clinical application and efficacy of ^(131)I therapy,so as to provide reference for clinical diagnosis and treatment of AFTN.