辽宁省35~75岁居民血脂异常患病情况及影响因素分析

Prevalence and influencing factors of dyslipidemia among the residents(35-75 years old)in Liaoning Province

目的了解辽宁省35~75岁城乡居民血脂异常流行情况及影响因素,为该地区的血脂异常防治提供科学依据。方法于2014年10月—2018年11月,采用多阶段分层整群抽样的方法选取辽宁省6市的6个县(区)常住居民136775人为调查对象,进行问卷调查、体格检查及实验室检测。应用SPSS 22.0进行χ^(2)检验、趋势χ^(2)检验及多因素logistic回归分析。结果辽宁省35~75岁居民的血脂异常患病率为37.00%,标化患病率为35.97%。高胆固醇血症、高甘油三酯血症、高低密度脂蛋白胆固醇血症和低高密度脂蛋白胆固醇血症的患病率分别为8.00%、22.09%、4.75%和16.26%,标化患病率分别为7.22%、21.22%、4.33%和16.55%。多因素logistic回归分析结果显示,女性(OR=1.043)、高年龄(与35~<45岁组相比,45~<55、55~<65、65~75岁的OR值分别为1.103、1.234、1.201)、城市(OR=1.301)、教育程度高(与小学及以下相比,大专及以上的OR=1.237)、家庭年收入≥5万元(OR=1.324)、现在吸烟(OR=1.225)、超重(OR=1.423)和肥胖(OR=2.316)、高血压(OR=1.754)均与辽宁省居民血脂异常患病高风险相关,均有统计学意义(P<0.01)。结论辽宁省35~75岁城乡居民血脂异常患病率较高,应加强对高血压的防控力度,加强对女性、高年龄、城市、高收入、高学历、吸烟、超重、肥胖及高血压患者的重点关注及综合干预。

Objective To understand the prevalence and influencing factors of dyslipidemia among the residents(35-75 years old)in Liaoning Province,and provide the scientific basis for prevention and treatment of dyslipidemia.Methods From October 2014to November 2018,the multi-stage stratified cluster random sampling method was used to select 136775 residents(35-75 years old)of 6 counties in Liaoning Province as the subjects.The investigation was performed with questionnaire,physical examination and laboratory tests.The t test,χ^(2)test and trendχ^(2)test were used to analyze the data,the multivariate non-conditional logistic regression analysis was used to analyze the influencing factors.The used software was SPSS 22.0.Results The morbidity of dyslipidemia in Liaoning residents(35-75 years old)was 37.00%.The standardized morbidity was 35.97%.The morbidities of hypercholesterolemia,hypertriglyceridemia,high low-density lipoprotein cholesterolemia and low high-density lipoprotein cholesterolemia were 8.00%,22.09%,4.75%and 16.26%,respectively,the standardized morbidities were 7.22%,21.22%,4.33%and 16.55%.respectively.Multivariate non-conditional logistic regression analysis showed that high age group(as compared with35-<45 years old group,45-<55 years old group OR=1.103,55-<65 years old group OR=1.234,65-<75 years old group OR=1.201),female(OR=1.043),urban residents(OR=1.301),higher educational level(as compared with primary school,college level OR=1.237),annual family income≥50000 yuan(OR=1.324),smoking(OR=1.225),overweight(OR=1.423),obesity(OR=2.316),and hypertension(OR=1.754)were related with high risk of dyslipidemia,P<0.01.Conclusion The morbidity of dyslipidemia among the residents(35-75 years old)in Liaoning Province is higher.The prevention and control measures for hypertension should be strengthened.The monitoring and comprehensive intervention of dyslipidemia for female,high age group,urban residents,high income and high educational residents,smoking,overweight,obesity,hypertension groups should be strengthened.