摘要
N^(6)-腺苷酸甲基化(N^(6)-methyladenosine,m^(6)A)修饰是真核生物中含量最丰富的RNA修饰,通过参与RNA的选择性剪接、稳定性、出核、翻译和降解等分子过程从而调控动物、植物和微生物的多项重要生物学功能。本文总结归纳了m^(6)A修饰在果蝇Drosophila、家蚕Bombyx mori、意大利蜜蜂Apis mellifera和烟粉虱Bemisia tabaci等昆虫生长发育、免疫和抗药性中的作用,并分析了当前研究中的不足与空白,为进一步研究m^(6)A修饰在昆虫中的生理功能提供参考。
N^(6)-methyladenosine(m^(6)A)modification is the most abundant RNA modification in eukaryotes.It regulates many important biological functions in animals,plants and microorganisms by affecting molecular processes such as RNA alternative splicing,stability,export,translation and degradation.In this review,we summarized the current research progresses in the roles of m^(6)A modification in the growth,development,immune and insecticide resistance in Drosophila,Bombyx mori,Apis mellifera,Bemisia tabaci and other insects,and analyzed the shortcomings and gaps in the current research in order to provide a reference for further research on the physiological functions of m^(6)A modifications in insects.
作者
张欣怡
白杨
郭乐
朱流红
苏奇
张友军
郭兆将
ZHANG Xinyi;BAI Yang;GUO Le;ZHU Liuhong;SU Qi;ZHANG Youjun;GUO Zhaojiang(College of Agriculture,Yangtze University,Jingzhou 434025,China;State Key Laboratory of Vegetable Biobreeding,Institute of Vegetables and Flowers,Chinese Academy of Agricultural Sciences,Beijing 100081,China)
出处
《植物保护》
CAS
CSCD
北大核心
2023年第5期221-228,242,共9页
Plant Protection
基金
国家自然科学基金(32372600,32022074,32172458,32221004)
蔬菜有害生物控制与优质栽培北京市重点实验室
中国农业科学院科技创新工程(CAAS-CSCB-202303)。
关键词
N^(6)-腺苷酸甲基化
表观遗传修饰
昆虫
生长发育
免疫
抗药性
N^(6)-methyladenosine
epigenetic modification
insects
growth and development
immune
insecticide resistance
