摘要
发展了一种铑催化碳酸亚乙烯酯与吲哚啉C(7)位C—H甲酰甲基化反应合成芳基乙醛化合物的高效方法.该反应条件温和,区域选择性专一,底物官能团兼容性好,产物收率较高.
A Rh(III)-catalyzed synthesis of arylacetaldehydes via C—H formylmethylation with vinylene carbonate has been developed.The reaction proceeded smoothly to give C7-functionalized N-(2-pyrimidyl)-indolines in moderate to good yields.This protocol features simple system,excellent regioselectivity,and good functional group compatibility.
作者
张彦波
孙萌
Zhang Yanbo;Sun Meng(Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education,College of Chemistry and Materials Science,Northwest University,Xi'an 710127)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2023年第8期2905-2912,共8页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21702160)资助项目.
关键词
铑催化
甲酰甲基化
吲哚啉
碳酸亚乙烯酯
rhodium catalysis
formylmethylation
indoline
vinylene carbonate
