基于MIL-101的莽草酸分子印迹聚合物的制备及应用

Preparation and Application of Shikimic Acid-Molecularly Imprinted Polymer Based on MIL-101

采用溶胶-凝胶法,以莽草酸为模板分子在金属有机框架材料MIL-101表面包覆分子印迹聚合物层,制备了一种对莽草酸具有特异性识别能力的核壳型分子印迹聚合物(MIP)。利用X射线衍射(XRD)、傅里叶红外光谱(FT-IR)、透射电子显微镜(TEM)等技术对聚合物进行表征,制备的MIL-101为八面体结构,表面均匀地包覆了分子印迹聚合物层。MIP的吸附性能测试结果显示,MIP在30 min达到吸附平衡,饱和吸附量为93.16 mg/g。MIP用作固相萃取吸附剂,表现出良好的选择性富集能力,能选择性分离和纯化八角中的莽草酸。

A core-shell molecularly imprinted polymer(MIP)possessing specific recognition for shikimic acid was prepared through the sol-gel method with metal organic framework MIL-101 as a substrate and shikimic acid as the template molecule.The MIP was characterized by a series of methods,including X-ray diffraction analysis(XRD),Fourier infrared spectroscopy(FTIR),and transmission electron microscopy analysis(TEM).The results showed that the prepared MIL-101 had octahedral structure and molecularly imprinted polymer shell was uniformly coated on it.The adsorption performance of MIP was evaluated through the adsorption experiment,and the MIP reached adsorption equilibrium within 30 min with a saturated adsorption capacity of 93.16 mg/g.The prepared polymer was used as a solid-phase extraction adsorbent,showing good selective enrichment ability,and could selectively isolate and purify the shikimic acid in the star anise.