摘要
羟基磷灰石/聚合物复合材料因为仿生细胞外基质,具有优良的生物活性、机械性能、可控降解性能、缓释功能,被广泛应用于骨修复领域。由于生长因子参与骨修复过程,因此羟基磷灰石/聚合物复合材料负载生长因子逐渐成为骨修复领域的研究热点之一。本文综述了近几年国内外羟基磷灰石/聚合物复合材料载生长因子在骨损伤或骨缺损治疗中的研究应用情况,并对其发展前景进行了展望。
Hydroxyapatite/polymer composites are widely used in the field of bone defect repair and bone regeneration due to their excellent bioactivity,mechanical properties,controllable degradation performance and slow-release property.Due to the involvement of growth factors in bone repair,hydroxyapatite/polymer composite loaded growth factors have gradually become one of the research hotspots in the field of bone repair.In this paper,the research and application of hydroxyapatite/polymer composite growth factors in the treatment of bone injury or bone defect in recent years were reviewed,and the development prospect of hydroxyapatite/polymer composite growth factors was discussed.
作者
齐军强
王浩田
叶晓健
许国华
QI Jun-qiang;WANG Hao-tian;YE Xiao-jian;XU Guo-hua(The Second Affiliated Hospital,Naval Medical University,Shanghai 200001,China;Tongren Hospital,Medical College,Shanghai Jiaotong University,Shanghai200336,China)
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2023年第17期1589-1593,共5页
Orthopedic Journal of China
基金
国家自然科学基金资助项目(编号:81972076,82102605)
国家重点研发计划资助项目(编号:2020YFC2008404)。
