基于数据挖掘的《中华医典》中脊痹的用药规律研究

Study on the medication rules of spinal bi in Chinese Medical Code based on data mining

目的基于数据挖掘技术分析《中华医典》所收录的治疗脊痹的内服处方的用药规律。方法以“脊痹、脊痛、脊脉痛、腰脊痛、脊中痛、腰脊强、腰脊病、脊强、背骨痛”为检索词,对《中华医典》中的所有处方进行检索,运用Excel 2016建立数据库,将数据进行规范后,对治疗脊痹的用药频数及性味归经及功效进行统计,运用SPSS Modeler 18.0、SPSS Statistics 20.0进行关联规则、聚类分析。结果共纳入脊痹相关方剂171首,中药265味。药物四气以温性为主,五味以甘、辛、苦味为主,归经以肝经为主,功效以补虚药为主。通过关联规则分析得到核心药物组合27组。通过聚类分析得到5组聚类方。结论以补虚扶正为主,兼以祛风散寒化湿、活血化瘀是《中华医典》治疗脊痹的用药规律。

Objective To analyze the medication rules of internal prescriptions for the treatment of spinal bi included in Chinese Medical Code based on data mining technology.Methods All the prescriptions in the Chinese Medical Code were searched with the search terms“spinal bi,spinal pain,spinal vessel pain,lumbar spinal pain,median spinal pain,lumbar spinal qiang,lumbar spinal disease,spinal qiang,and back bone pain”,and Excel 2016 was used to establish a database.After the data were normalized,the frequency,nature,flavour,channel tropism,and the efficacy of medication of the treatment of spinal bi were analyzed.SPSS Modeler 18.0 and SPSS Statistics 20.0 were used for association rules and cluster analysis.Results A total of 171 spinal bi related prescriptions and 265 kinds of Chinese materia medica were included.The four nature of drugs were mainly warm,the five flavours of drugs were mainly sweet,pungent,and bitter,the channel tropism of drugs were mainly liver channel,and the efficacy of the drugs were mainly deficiency tonifying drug.Twenty-seven core drug combinations were obtained by association rule analysis.Five groups of clustering methods were obtained by cluster analysis.Conclusion The principle of tonifying deficiency and strengthening vital qi as main,as well as dispelling wind and dispelling cold and dispelling dampness,promoting blood circulation for removing blood stasis are the rules of the Chinese Medical Code.