腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的疗效研究

Study on efficacy of laparoscopic myomectomy in the treatment of hysteromyoma

目的研究腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的临床疗效。方法76例子宫肌瘤患者,按照入院先后顺序分为对照组和实验组,每组38例。对照组患者使用传统开腹手术治疗,实验组患者使用腹腔镜子宫肌瘤剔除术治疗。对比两组患者术中、术后情况及卵巢储备功能指标[促卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E_(2))]、术后并发症发生情况。结果实验组术中出血量(34.57±9.03)ml少于对照组的(86.08±12.79)ml,手术时间(48.63±3.67)min、术后排气时间(12.36±3.11)h、术后下床活动时间(24.74±3.09)h、住院时间(5.12±0.87)d短于对照组的(79.56±9.06)min、(26.01±2.65)h、(35.13±4.54)h、(9.41±2.36)d,视觉模拟评分法(VAS)评分(4.54±1.79)分低于对照组的(7.14±1.33)分,差异有统计学意义(P<0.05)。实验组FSH(6.13±0.78)U/L、LH(7.13±1.21)U/L、E_(2)(41.23±6.13)pg/ml均显著低于对照组的(8.16±0.97)U/L、(7.94±1.41)U/L、(47.14±8.03)pg/ml,差异有统计学意义(P<0.05)。实验组术后并发症发生率2.63%低于对照组的26.32%,差异有统计学意义(P<0.05)。结论腹腔镜子宫肌瘤剔除术治疗子宫肌瘤患者的效果较好,患者术中术后各指标较优,术后并发症较少,值得推广使用。

Objective To study the clinical efficacy of laparoscopic myomectomy in the treatment of hysteromyoma.Methods A total of 76 patients with hysteromyoma were divided into control group and experimental group according to the order of admission,with 38 cases in each group.The control group was treated with traditional open surgery,and the experimental group was treated with laparoscopic myomectomy.Both groups were compared in terms of intraoperative and postoperative conditions,ovarian reserve function indexes[follicle-stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2))],and postoperative complications.Results The intraoperative blood loss of(34.57±9.03)ml in the experimental group was less than that of(86.08±12.79)ml in the control group;in the experimental group,the operative duration was(48.63±3.67)min,the postoperative exhaust time was(12.36±3.11)h,the postoperative ambulation time was(24.74±3.09)h,and the hospitalization time was(5.12±0.87)d,which were shorter than those of(79.56±9.06)min,(26.01±2.65)h,(35.13±4.54)h,and(9.41±2.36)d in the control group;the visual analogue scale(VAS)score of(4.54±1.79)points in the experimental group was lower than that of(7.14±1.33)points in the control group;the differences were statistically significant(P<0.05).The experimental group had FSH of(6.13±0.78)U/L,LH of(7.13±1.21)U/L,and E_(2) of(41.23±6.13)pg/ml,which were significantly lower than those of(8.16±0.97)U/L,(7.94±1.41)U/L,and(47.14±8.03)pg/ml in the control group,and the differences were statistically significant(P<0.05).The incidence of postoperative complications of 2.63%in the experimental group was lower than that of 26.32%in the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic myomectomy has a good effect in the treatment of patients with hysteromyoma,with excellent intraoperative and postoperative indexes and less postoperative complications,which is worthy of popularization.