肾移植器官保存研究进展

Advances in organ preservation during kidney transplantation

维持器官保存期间供肾的活力是器官移植成功的前提条件和根本保障。目前,单纯低温保存仍是各大器官移植中心首选且最常用的保存方法。随着供体需求量的增加,越来越多的老年供体和边缘供体被用于临床,这对传统的器官保存方法提出了更高的要求。该文着重对肾移植器官保存液及器官机械灌注的最新进展进行综述。

Maintaining the vitality of the donor kidney during organ preservation is the prerequisite and the fundamental guarantee for successful organ transplantation.At present,cold storage(CS)is still the preferred and the most commonly used preservation method in the majority of organ transplant centers.With the increasing demand for donors,more and more elderly and marginal donors have been used in clinical practice,which puts higher demands on traditional organ preservation approaches.This review focuses on the latest progress in organ preservation solutions and machine perfusion for kidney transplantation.