摘要
炭类中药是中医药体系中最具特色的中药炮制品之一,长久以来广泛应用于各种出血性疾病治疗中且疗效突出。近年来,诸多学者从各个角度对炭类中药的止血作用机制进行了相关研究,并取得了一定的成果,但是却无法从整体上阐释炭类中药共有的止血作用。文章基于中性粒细胞外陷阱的血管闭塞机制,尝试从理论上解释不同来源的炭类中药如何通过这一共有机制发挥止血作用。
As one of the most distinctive herbal processed products in the Chinese medicine system,charcoal Chinese medicine has long been widely used in various bleeding disorders with outstanding efficacy.In recent years,many scholars have conducted studies on the mechanism of the hemostatic effect of charcoal Chinese medicine from various perspectives and have achieved certain results,but the common hemostatic effect of charcoal Chinese medicine is still unclear.The mechanism of vascular occlusion based on neutrophil extracellular trap could theoretically explain how different sources of charcoal Chinese herbs could exert hemostatic effects through this common mechanism.
作者
蔡明阳
陈香云
谭雯
孙艺凡
刘珍洪
佟海英
杨桢
CAI Mingyang;CHEN Xiangyun;TAN Wen;SUN Yifan;LIU Zhenhong;TONG Haiying;YANG Zhen(School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 102488,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2023年第9期4488-4491,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
内蒙古自治区科技重大专项课题(No.2019ZD004)
国家自然科学基金项目(No.82104822)
蒙药研发国家地方联合工程研究中心开放基金项目(No.MDK2020005)。
关键词
炭类中药
中性粒细胞外陷阱
炭黑颗粒
微/纳米颗粒
止血
原理
血管闭塞机制
Charcoal Chinese medicine
Neutrophil extracellular traps
Carbon black
Nano/micro particles
Hemostatic
Principle
Mechanism of vascular occlusion
