颞下颌关节二水焦磷酸钙结晶沉积症1例报告及文献复习

Calcium pyrophosphate dihydrate crystal deposition disease of the temporomandibular joint: case report and literature review

二水焦磷酸钙结晶沉积症(calcium pyrophosphate dihydrate crystal deposition disease,CPPD)是指焦磷酸钙结晶沉积于关节内纤维软骨、透明软骨及其周围滑膜、韧带、肌腱、关节囊的总称。CPPD在多数患者中表现为特发,但其与衰老、骨关节炎、痛风、甲状旁腺功能亢进以及血色素沉着症和低镁血症等代谢性疾病有关。本文报告1例颞下颌关节二水焦磷酸钙结晶沉积症女性病例,病损侵及颞下颌关节髁突、关节盘和颅底,手术切除病损并重建颅底和颞下颌关节。

Calcium pyrophosphate dihydrate crystal deposition disease(CPPD)refers to calcium pyrophosphate crystals deposited in articular fibrocartilage,hyaline cartilage and its surrounding synovium,ligaments,tendons and joint capsules.CPPD is idiopathic in most patients,however,it has been associated with aging,osteoarthritis,gout,hyperparathyroidism and metabolic disorders like hemochromatosis and hypomagnesemia.In this paper,a female patient with CPPD of temporomandibular joint(TMJ)was reported,in which the lesion invaded cranial base,the condyle and disc of TMJ.Surgical procedure was performed to remove the lesion and reconstruct cranial base and TMJ.