基于拉曼光谱的膀胱癌诊断研究进展

Advances in the diagnosis of bladder cancer based on Raman spectroscopy

膀胱癌是泌尿系统常见的肿瘤之一,早发现早治疗可以降低复发率和病死率。目前传统检查手段的诊断特异性和敏感性难以兼顾,而拉曼光谱技术作为一种分子诊断技术,能够在分子水平揭示正常膀胱尿路上皮组织和膀胱尿路上皮癌之间的差异,较传统诊断技术具有诊断速度快且精确的特点。本文对拉曼光谱技术诊断膀胱癌的研究进展进行综述。

Bladder cancer is one of the common tumors of urinary system.Early detection and treatment can reduce the recurrence rate and mortality.Currently,it is difficult to balance the diagnostic specificity and sensitivity of traditional diagnostic methods.However,Raman spectroscopy,as a molecular diagnostic technology,can reveal the difference between normal urinary tract epithelial tissue and urinary tract epithelial cell carcinoma of the bladder at the molecular level,which has the characteristics of faster and more accurate diagnosis compared with traditional diagnostic techniques.This paper reviews the research progress of Raman spectroscopy in the diagnosis of bladder cancer.