综合干预在乌司他丁治疗急性胰腺炎期间的效果观察

Observation on the Effect of Comprehensive Intervention in Acute Pancreatitis Patients Treated with Ulinastatin

目的:探讨综合干预在乌司他丁治疗急性胰腺炎中的应用效果。方法:选择本院2020年8月—2022年12月收治的92例急性胰腺炎患者为研究对象,按双色球随机法分为对照组和观察组,各46例。所有研究对象均采用乌司他丁治疗,对照组给予常规干预,观察组给予综合干预,比较两组用药依从性、不良反应发生率及用药合理率。结果:干预后,观察组用药依从率为97.50%,高于对照组的77.50%(P<0.05);观察组不良反应发生率为5.00%,低于对照组的25.00%(P<0.05);观察组患者合理用药率为95.00%,高于对照组的75.00%(P<0.05)。结论:综合干预在乌司他丁治疗急性胰腺炎中的应用效果显著,可降低不良反应发生率,提升患者合理用药率,值得临床应用。

Objective:To explore the application effect of comprehensive intervention in acute pancreatitis patients treated with ulinastatin.Methods:A total of 92 patients with acute pancreatitis admitted to our hospital from August 2020 to December 2022 were selected as the study subjects.They were randomly divided into a control group and an observation group using a two-color ball method,with 46 patients in each group.All research subjects were treated with ulinastatin.The control group received routine intervention,while the observation group received comprehensive intervention.The medication compliance,incidence of adverse reactions,and rational use of medication were compared between the two groups.Results:After intervention,the medication compliance rate in the observation group was 97.50%,which was higher than 77.50%in the control group(P<0.05).The incidence of adverse reactions in the observation group was 5.00%,which was lower than 25.00%in the control group(P<0.05).The reasonable medication rate of patients in the observation group was 95.00%,which was higher than 75.00%in the control group(P<0.05).Conclusion:The application of comprehensive intervention in acute pancreatitis patients treated with ulinastatin has a significant effect,which can reduce the incidence of adverse reactions,improve the rational drug use rate of patients,and is worthy of clinical application.