理金安肺汤治疗老年肺小结节患者的临床观察

Clinical observation of Lijin Anfei Decoction in treating elderly patients with pulmonary nodules

目的 观察理金安肺汤对老年肺小结节的疗效。方法 选取复旦大学附属华东医院中医内科门诊2018年1月~2021年12月收治的老年肺小结节患者180例作为研究对象,按照随机数字表法分为两组,治疗组120例,对照组60例。治疗组给予理金安肺汤治疗,对照组以定期随访胸部CT为主。比较两组结节病灶和中医临床症状评分的变化情况,并进行疗效评价。结果 治疗组肺结节大小总体疗效优于对照组(P<0.05),其中治疗组孤立实性结节、孤立磨玻璃结节、孤立混合结节患者经治疗后结节大小疗效优于对照组(P<0.05)。治疗组中医临床症状总有效率高于对照组(P<0.05),其中治疗组孤立实性结节、孤立磨玻璃结节、多发结节患者的中医症状总有效率均高于对照组(P<0.05)。经综合评价,治疗组总有效率高于对照组(P<0.05)。结论 理金安肺汤能够明显改善老年肺小结节患者的临床症状,是一种有效的临床治疗方法。

Objective To observe the fficacy of Lijin Anfei Decoction in treating elderly patients with pulmonary nodules.Methods 180 elderly patients with pulmonary nodules admitted to the Department of Traditional Chinese Mediceine of Huadong Hospi-tal afliated to Fudan University from January 2018 to December 2021 were selected as the research objects.They were randomly di-vided into two groups using a random digital table,with 120 patients in the treatment group and 60 patients in the control group.The treatment group was given Lijin Anfei Decoction,while the control group was mainly followed up with regular chest CT scans.The changes in the nodular lesions and TCM clinical symptom scores were compared between the two groups,and the fficacy was evalua-ted.Results The overall therapeutic effect on lung nodules was better in the treatment group than in the control group(P<0.05),with better efficacy in the treatment group for isolated solid nodules,isolated ground-glass nodules,and isolated mixed nodules(P<0.05).The total effective rate of TCM elinical symptoms in the treatment group was higher than that in the control group(P<0.05),with higher total effective rates in the treatment group for isolated solid nodules,isolated ground-glass nodules,and multiple nodules(P<0.05).After comprehensive evaluation,the total effective rate in the treatment group was higher than that in the control group(P<0.05)。Conclusion Li Jin Anfei Decoction can significantly improve the clinical symptoms of elderly patients with pul-monary nodules,and is an effective clinical treatment method.