国内首报色素性大汗腺错构瘤1例

Pigmented apocrine hamartoma: the first case reported in China

患儿女,9岁,被发现外阴部无症状不规则黑褐色丘疹2周,临床拟诊色素痣,行手术切除治疗。术后组织病理检查:真皮内扩张的腺体及管腔,管腔内可见嗜酸性分泌物及色素颗粒,内层细胞可见断头分泌现象,管腔外周为扁平的肌上皮细胞;腺体及管腔上皮内、间质内含大量棕黑色色素,间质内淋巴细胞、浆细胞浸润。诊断为色素性大汗腺错构瘤。

A 9-year-old girl presented with a symptomless irregular dark brown papule on the vulva for 2 weeks.The patient was initially clinically diagnosed with pigmented nevus,and underwent surgical excision.Postoperative histopathological examination showed dilated glands and tubules in the dermis,eosinophilic secretions and pigment granules in the tubules,decapitation secretion in the inner layer cells,and flat myoepithelial cells around the tubules;a large amount of brown-black pigments were seen in the glands,tubular epithelium and interstitium,and lymphocytes and plasma cells infiltrated the interstitium.Finally,the diagnosis of pigmented apocrine hamartoma was made.