浙派中医赵献可治疗女科病用药规律与特色浅析

Brief Analysis of Medication Rules and Characteristics of ZHAO Xianke of Zhejiang School of Chinese Medicine in Treating Female Diseases

目的:基于数据挖掘技术探讨浙派中医赵献可治疗女科病用药规律与特色。方法:运用中医传承辅助平台V2.5、SPSS Modeler等软件,采用频次统计、关联规则、聚类分析等数据挖掘方法,对赵献可《邯郸遗稿》所载女科病方剂进行分析。结果:共收集方剂222首,中药223味。其中频次≥20的中药有19味,排在前5的分别为甘草、当归、川芎、茯苓、人参;四气频次中温性药最高,其次是平性药、寒性药等;五味频次统计中辛味最高,其次是甘味、苦味等。归经排在前五位分别为脾、肺、心、肝、胃经。药物关联规则分析频次≥30的组合有21组,药物组方规律分析得出12个核心药物组合和6首新处方。结论:通过数据挖掘分析得出赵献可治疗女科病方剂以甘辛温补为主,重视肝脾、肝肾的调治,并配合疏肝、清肝、抑肝等治法,可为临床治疗女科病提供一定的参考。

Objective:To explore the administration rule and characteristics of ZHAO Xianke of Zhejiang School of Chinese Medicine in treating female diseases based on data mining technology.Methods:By Traditional Chinese Medicine Inheritance Assistance Platform V2.5,SPSS Modeler and other software and through data mining methods of frequency statistics,association rules and cluster analysis,the prescriptions recorded to treat female diseases in ZHAO Xianke's Handan Posthumous Manuscript were analyzed.Results:A total of 222 prescriptions and 223 kinds of Chinese herbs were collected.Among them,there were 19 Chinese herbs with frequency of 20 or over 20,and the top 5 were Glycyrrhizae Radix et Rhizoma,Angelicae Sinensis Radix,Chuanxiong Rhizoma,Poria and Ginseng Radix et Rhizoma.In terms of four qi,the frequency of warm herbs was the highest,followed by mild herbs and cold herbs.In terms of five tastes,the frequency of acrid herbs was the highest,followed by sweet herbs and bitter herbs.The top 5 channel entries were the spleen,lung,heart,liver and stomach.There were 21 groups of drug association rule analysis with frequency greater than or equal to 30 times,and 12 core drug combinations and 6 new prescriptions were obtained from the analysis of drug prescription rules.Conclusion:Through data mining analysis,it is concluded that,in treating patients with female diseases,ZHAO Xianke mainly used sweet and acrid herbs to warm and supplement,and focused on the regulation of the liver and spleen,and the liver and kidney.He also combined with the methods of soothing the liver,clearing the liver,inhibiting the liver.His prescriptions provided a certain reference for the clinical treatment of female diseases.