一起幼儿园札如病毒感染疫情调查分析

Investigation and analysis of an epidemic of Zaru virus infection in a kindergarten

目的对一起幼儿园内札如病毒引起的聚集性疫情进行流行病学调查和病原学检测,为札如病毒的防控提供依据。方法通过流行病学调查,核实搜索病例,分析疫情特征。采集肛拭子标本,运用三重实时荧光PCR法(RT-PCR)检测诺如病毒、轮状病毒、札如病毒、腺病毒和星状病毒等常见肠道病毒核酸。结果共检索到疑似病例13例,罹患率59.09%(13/22)。13例病例均集中在KC3班。采集7例病例的肛拭子进行病毒核酸检测,5份样本札如病毒核酸阳性,其中1份样本札如病毒与腺病毒核酸双阳性,其余病毒核酸均为阴性。结论本次疫情是由札如病毒引起,需要提高幼儿园教师和家长防病意识,加大学校传染病防控力度,有效控制札如病毒传播。

Objective To conduct an epidemiological investigation and etiological detection of a cluster of outbreaks caused by Zaru virus in a kindergarten,so as to provide evidence for the prevention and control of the spread of the epidemic.Methods Through epidemiological investigation,the searched cases were verified and the characteristics of the epidemic were analyzed.Swab specimens were collected and detected for common enteroviral nucleic acids of norovirus,rotavirus,Zaru virus,adenovirus,and astrovirus by using triple real-time fluorescence PCR(RT-PCR).Results A total of 13 suspected cases were retrieved,with a prevalence rate of 59.09%(13/22).All 13 cases are concentrated in the KC3 class.The swabs from 7 cases were collected for viral nucleic acid testing,and 5 samples were positive for Zaru virus nucleic acid,of which 1 sample was positive for Zaru virus and adenovirus nucleic acid,but the rest were negative for viral nucleic acid.Conclusions This cluster outbreak is caused by Zaru virus.Therefore,it is necessary to improve the awareness of kindergarten teachers and parents on disease prevention,and strengthen the prevention and control measures of infectious diseases in schools,so as to effectively control the spread of Zaru virus.