全面性发育迟缓儿童头颅MRI特征探讨

Study on Cranial MRI Characteristics of Children with Global Development Delay

目的探讨全面性发育迟缓儿童的头颅MRI特征。方法以诊断为依据,回顾性纳入了符合标准的313例全面性发育迟缓的头颅MRI,分析了全面性发育迟缓患儿头颅MRI的表现、异常率、异常率与Gesell分级之间的关系。结果全面性发育迟缓儿童头颅MRI异常率为57.19%,全面性发育迟缓头颅MRI异常的各种表现中,以脑白质髓鞘化异常最为多见,66例,占36.87%;其次为脑外间隙增宽和脑室增大,47例,占26.26%,头颅MRI异常率与Gesell分级有关:2=33.20,P<0.01。结论脑白质髓鞘化异常、脑外间隙增宽和脑室增大是GDD患儿常见的MRI表现,MRI对于中、重度GDD患儿的异常显示率较高,具有较高的诊断价值。

Objective to explore the cerebral palsy and mental retardation children head MRI characteristics.Methods based on diagnosis,were brought into standard 796 cases 1076 cases of cerebral palsy and mental retardation head MRI,analysis of cerebral palsy and mental retardation head MRI abnormalities rate between the two diseases,and respectively with GMFCS grading and the relationship between the degree of intelligence.Results The results of cerebral palsy and mental retardation children head MRI abnormality rate,χ^(2)=543.692,P<0.001,both statistically significant;Cerebral palsy children head MRI abnormality rate trend with the GMFCS hierarchical relationship,χ^(2)=181.88,P<0.0001,head MRI abnormality rate increased as the GMFCS grading increases,ⅣandⅤχ^(2)=0.414,P value=0.52>0.05,no statistical differences between the two,may be associated with the pathogenesis of cerebral palsy.Mental retardation children has nothing to do with mental retardation dividing head MRI abnormality rate:χ^(2)=1.536,P=0.214>0.05;Cerebral palsy in the cranial MRI abnormality is one of the most common ventricle softening around the see more,468 cases,accounting for 52.71%;Followed by multiple softening and shrinking,with 178 cases,accounting for 21.76%.Mental retardation head MRI abnormalities of various kinds of performance,with the most cerebral white matter abnormalities myelination more see,67 cases,accounting for 41.88%;Followed by outside clearance increases the width,and brain ventricle,38 cases,accounting for 23.75%.Conclusion cranial MRI on cerebral palsy children with pathological mechanism,predict prognosis has important value,is more important than children with mental retardation.