抗阻训练联合高乳蛋白营养在老年2型糖尿病伴肌少症病人中的应用研究

Application of resistance training combined with high milk protein nutrition in elderly patients with type 2 diabetes mellitus and sarcopenia

目的探究抗阻训练联合高乳蛋白营养对老年T2DM伴肌少症病人的应用效果。方法选择2021年1月至2022年1月期间我院收治的老年T2DM伴肌少症病人78例作为研究对象,随机分成2组,每组39例,对照组予以常规治疗,研究组在对照组的基础上进行抗阻训练联合高乳蛋白营养干预。比较2组病人静息状态下骨骼肌质量指数、握力、FPG和HbA1c水平、生活质量及跌倒发生率。结果干预后研究组骨骼肌质量指数与握力均高于干预前,且与对照组比较,差异均有统计学意义(P<0.05);2组干预后FPG和HbA1c水平均明显降低,且研究组改善更明显,差异有统计学意义(P<0.05);研究组干预后生活质量各维度得分均高于干预前(P<0.05),且研究组生理功能、生理职能、总体健康、精神健康各维度得分均高于对照组(P<0.05);研究组跌倒发生率明显低于对照组(5.13%比23.08%,P<0.05)。结论抗阻训练联合高乳蛋白营养能显著提高老年T2DM伴肌少症病人骨骼肌质量指数与握力,降低病人血糖,提高病人生活质量且降低跌倒发生率。

Objective To explore the effect of resistance training combined with high milk protein nutrition in the elderly patients with type 2 diabetes mellitus(T2DM)and sarcopenia.Methods A total of 78 elderly patients with T2DM and sarcopenia admitted to our hospital from January 2021 to January 2022 were selected as the study subjects,and were randomly divided into two groups,with 39 cases in each group.The control group received routine treatment,while the study group received resistance training combined with high milk protein nutrition intervention on the basic treatment of the control group.The skeletal muscle mass index,grip strength,fasting plasma glucose(FPG),glycated hemoglobin(HbA1c),quality of life(QOL)and the incidence of falls in two groups were observed and compared.Results After intervention,the levels of skeletal muscle mass index and grip strength in the study group were significantly higher than those before intervention and those in the control group(P<0.05).The levels of FPG and HbA1c were significantly decreased in two groups after intervention,especially in the study group(P<0.05).After intervention,the scores of QOL of all dimensions were significantly higher than those before intervention in the study group(P<0.05),and the scores of physiological function,role physical,overall health,and mental health in the study group were higher than those in the control group(P<0.05).The incidence rate of falls in the study group was lower than that in the the control group(5.13%vs 23.08%,P<0.05).Conclusions Resistance training combined with high milk protein nutrition can significantly improve the skeletal muscle mass index and grip strength of the elderly T2DM patients with sarcopenia,reduce blood glucose,improve the QOL of the patients and reduce the incidence of falls.