冠脉搭桥术后患者心肌做功指数变化及与左心室质量指数、左心室射血分数的相关性

Changes in Myocardial Work Index and Its Correlation with LVMI and LVEF in Patients after Coronary Artery Bypass Grafting Surgery

目的探讨冠脉搭桥术后患者心肌做功指数(Tei指数)变化及与左心室质量指数(LVMI)、左心室射血分数(LVEF)的相关性。方法选取2020年1月至2022年12月医院收治的60例行冠脉搭桥术患者为观察组,另选取同期健康体检的志愿者60名作为对照组。比较两组Tei指数、LVMI、LVEF指标情况,统计观察组术后良好患者与不良患者术前、术后4周及12周各时间点Tei指数、LVMI、LVEF指标变化,并采用Pearson相关系数分析患者Tei指数与LVMI、LVEF指标的相关性。结果观察组Tei指数、LVMI指标均高于对照组,LVEF指标低于对照组,差异有统计学意义(P<0.05);良好组患者术后4周Tei指数、LVMI指标低于术前,LVEF指标高于术前,差异有统计学意义(P<0.05);术后12周Tei指数、LVMI指标低于术后4周,LVEF指标高于术后4周,差异有统计学意义(P<0.05);不良组患者术后4周Tei指数、LVMI及LVEF指标与术前比较,差异无统计学意义(P>0.05),术后12周时Tei指数、LVMI指标低于术前及术后4周,LVEF指标高于术前及术后4周,差异有统计学意义(P<0.05);但良好组患者术后4、12周时,Tei指数、LVMI指标低于术后不良组,LVEF指标高于术后不良组,差异有统计学意义(P<0.05);经Pearson相关系数分析结果显示,冠脉搭桥术后患者Tei指数与LVMI指标呈正相关(r=0.624,P<0.05),与LVEF呈负相关(r=-0.643,P<0.05)。结论冠脉搭桥术后患者Tei指数、LVMI总体均呈下降趋势,LVEF呈上升趋势,3者具有密切的相关性。

Objective The changes in myocardial work index(Tei index)and its correlation with left ventricular mass index(LVMI)and left ventricular ejection fraction(LVEF)in patients after coronary artery bypass grafting surgery were investigated.Methods With the selection of 60 patients undergoing coronary artery bypass grafting surgery admitted to the hospital from January 2020 to December 2022 as the observation group,and 60 volunteers who underwent physical examinations during the same period as the control group,the Tei index,LVMI,and LVEF indicators were compared between the two groups.The changes in Tei index,LVMI,and LVEF indicators at various time points before,4 weeks,and 12 weeks after surgery were statistically analyzed for both good and bad postoperative patients in the observation group.In addition,Pearson correlation coefficient was used to analyze the correlation between Tei index and LVMI,LVEF indicators in patients.Results The Tei index and LVMI index of the observation group were higher than those of the control group,while the LVEF index was lower than that of the control group,with statistically significant differences(P<0.05);The Tei index and LVMI index of patients at 4 weeks after surgery in the good group were lower than those before surgery,while LVEF index was higher than those before surgery,with statistically significant differences(P<0.05);The Tei index and LVMI index at 12 weeks after surgery were lower than those at 4 weeks after surgery,while the LVEF index was higher than those at 4 weeks after surgery,with statistically significant differences(P<0.05);There was no statistically significant difference in Tei index,LVMI,and LVEF indicators between the adverse group patients at 4 weeks after surgery and before surgery(P>0.05),and at 12 weeks after surgery,Tei index and LVMI index were lower than before and 4 weeks after surgery,while LVEF index was higher than before and 4 weeks after surgery,with statistically significant differences(P<0.05);However,at 4 and 12 weeks after surgery,the Tei index and LVMI index in the good group were lower than those in the postoperative adverse group,while the LVEF index was higher than those in the postoperative adverse group,with statistically significant differences(P<0.05);The Pearson correlation coefficient analysis showed that the Tei index of patients after coronary artery bypass grafting was positively correlated with LVMI indicators(r=0.624,P<0.05),and negatively correlated with LVEF(r=-0.643,P<0.05).Conclusion After coronary artery bypass grafting surgery,the Tei index and LVMI of patients showed an overall downward trend,while LVEF showed an upward trend,indicating a close correlation between the three.