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新型植物源天然产物杀虫剂研究进展 被引量:3

Research progress of novel botanical insecticides
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摘要 与传统化学杀虫剂相比,植物源天然产物杀虫剂具有靶标特异性强、易降解无残留、对环境无污染等优点,符合绿色农业的发展要求,是杀虫剂研发的重要领域之一。本文围绕不同类型植物源天然产物杀虫剂的结构特征和作用机制,综述了2015年之后以植物源杀虫剂活性成分为先导化合物进行结构改造的研究现状,最后对植物源农药的发展方向、当前面临的挑战以及产品研发策略进行了分析和展望。 Natural product-derived botanical insecticides have the advantages of strong target specificity,easy degradation,pesticide residue free and no pollution to the environment compared to the traditional chemical insecticides.They meet the development requirements of green agriculture and are one of the important research and development fields of insecticides.In this paper,the current status of the research and development of botanical natural product insecticides as lead compounds for structural modification since 2015 were reviewed.Finally,the trends of future development,current challenges and the subsequent research strategy of botanical insecticides were analyzed and prospected.
作者 董小绮 康兆勇 刘胜男 高清志 DONG Xiaoqi;KANG Zhaoyong;LIU Shengnan;GAO Qingzhi(Frontiers Science Center for Synthetic Biology,School of Pharmaceutical Science and Technology,Tianjin Key Laboratory for Modern Drug Delivery&High-Efficiency,Tianjin University,Tianjin 300072,China;Institute of Molecular Plus,Tianjin University,Tianjin 300072,China)
出处 《农药学学报》 CAS CSCD 北大核心 2023年第5期969-989,共21页 Chinese Journal of Pesticide Science
基金 国家重点研发计划项目(2020YFA0907903).
关键词 植物源天然产物 杀虫剂 结构修饰 作用机制 构效关系 botanical natural products insecticides structural modification mechanism of action structure-activity relationship
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